Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 20/20 | 0.54 |
| ▸ | F10 | P00742 | 3/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.47 |
| ▸ | F12 | P00748 | 1/20 | 0.44 |
| ▸ | F7 | P08709 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7375268 | 0.85 | F2 (0.60) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL7380017 | 0.84 | F2 (0.61) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL7379392 | 0.84 | F2 (0.61) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL7372916 | 0.84 | F2 (0.54) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL7378127 | 0.83 | F2 (0.51) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL7379487 | 0.83 | F2 (0.54) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL6920901 | 0.82 | F2 (0.50) | F2F10PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL6919984 | 0.81 | F2 (0.51) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL7378892 | 0.79 | F2 (0.47) | F2F10PRSS1 | |
| SCHEMBL7378295 | 0.79 | F2 (0.62) | F2F10PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002050056-A1 | BENZYLAMINE DERIVATIVES AND THEIR USE AS THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 2002-06-27 | — | — | WO | disclosed |