Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 8/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 8/20 | 0.47 |
| ▸ | PDE4A | P27815 | 7/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 7/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7465654 | 1.00 | PDE4B (0.47) | PDE4BPDE4DPDE4APDE4CGAA | |
| SCHEMBL7384149 | 0.92 | PDE4B (0.47) | PDE4BPDE4DPDE4APDE4CGAA | |
| SCHEMBL7384154 | 0.92 | PDE4B (0.47) | PDE4BPDE4DPDE4APDE4CGAA | |
| SCHEMBL7379302 | 0.90 | PDE4B (0.52) | PDE4BPDE4DPDE4APDE4CPDE5A | |
| SCHEMBL7379306 | 0.90 | PDE4B (0.52) | PDE4BPDE4DPDE4APDE4CPDE5A | |
| SCHEMBL7379304 | 0.90 | PDE4B (0.52) | PDE4BPDE4DPDE4APDE4CPDE5A | |
| SCHEMBL7470164 | 0.87 | PDE4B (0.43) | PDE4BPDE4DPDE4APDE4CGAA | |
| SCHEMBL7470157 | 0.87 | PDE4B (0.43) | PDE4BPDE4DPDE4APDE4CGAA | |
| SCHEMBL7468632 | 0.84 | PDE4D (0.51) | PDE4BPDE4DPDE4APDE4CPDE5A | |
| SCHEMBL7468624 | 0.84 | PDE4D (0.51) | PDE4BPDE4DPDE4APDE4CPDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889879-B1 | BUTADIENE DERIVATIVES AND PROCESS FOR PREPARING THEREOF | TANABE SEIYAKU CO (JP) | 2002-06-12 | — | — | EP | disclosed |
| US-6248743-B1 | ANTITHROMBOTIC AGENTS EFFECTIVE TO INHIBIT THE PRODUCTION OF TYPE 1 PLASMINOGEN ACTIVATOR INHIBITOR (PAI-1) | TANABE SEIYAKU CO., LTD. (JP) | 2001-06-19 | — | — | US | disclosed |