Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.56 |
| ▸ | CCR3 | P51677 | 6/20 | 0.41 |
| ▸ | CCR1 | P32246 | 4/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | PRCP | P42785 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7469198 | 0.97 | MCHR1 (0.53) | MCHR1CCR3CCR1BCHEDRD2 | |
| SCHEMBL7463105 | 0.92 | MCHR1 (0.65) | MCHR1CCR3CCR1SIGMAR1HTR7 | |
| SCHEMBL7462069 | 0.92 | MCHR1 (0.59) | MCHR1CCR3CCR1SIGMAR1PRCP | |
| Hydrochloric Acid SCHEMBL7463703 | 0.91 | MCHR1 (0.64) | MCHR1CCR3SIGMAR1HTR7CCR5 | |
| SCHEMBL7459739 | 0.90 | MCHR1 (0.55) | MCHR1CCR3DRD2SIGMAR1OPRM1 | |
| SCHEMBL7458844 | 0.88 | MCHR1 (0.56) | MCHR1CCR3CCR1BCHEDRD2 | |
| Hydrochloric Acid SCHEMBL7465359 | 0.87 | MCHR1 (0.56) | MCHR1CCR3CCR1BCHEDRD2 | |
| Hydrochloric Acid SCHEMBL7467702 | 0.87 | MCHR1 (0.56) | MCHR1DRD2CCR2 | |
| SCHEMBL7453896 | 0.87 | MCHR1 (0.53) | MCHR1CCR3CCR1SIGMAR1HTR7 | |
| Hydrochloric Acid SCHEMBL7465870 | 0.86 | MCHR1 (0.59) | MCHR1SIGMAR1HTR7CCR5PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | claimed |
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |