Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 6/20 | 0.43 |
| ▸ | TACR1 | P25103 | 6/20 | 0.43 |
| ▸ | TACR3 | P29371 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7472607 | 0.94 | TACR1 (0.44) | TACR2TACR1HRH1 | |
| SCHEMBL7462814 | 0.94 | TACR2 (0.42) | TACR2TACR1TACR3HRH1 | |
| SCHEMBL7467628 | 0.93 | TACR2 (0.48) | TACR2TACR1TACR3HRH1 | |
| SCHEMBL7466184 | 0.93 | TACR2 (0.44) | TACR2TACR1TACR3HRH1 | |
| SCHEMBL7464193 | 0.93 | TACR2 (0.42) | TACR2TACR1TACR3HRH1 | |
| SCHEMBL7461456 | 0.93 | TACR2 (0.45) | TACR2TACR1TACR3HRH1 | |
| SCHEMBL7473600 | 0.92 | TACR2 (0.43) | TACR2TACR1TACR3HRH1 | |
| SCHEMBL7461841 | 0.92 | TACR2 (0.52) | TACR2TACR1TACR3HRH1 | |
| SCHEMBL7460834 | 0.92 | TACR2 (0.52) | TACR2TACR1TACR3HRH1 | |
| SCHEMBL7462445 | 0.92 | TACR2 (0.52) | TACR2TACR1TACR3HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946548-B1 | NOVEL HETEROCYCLIC SUBSTITUTED PYRROLIDINE AMIDE DERIVATIVES | AVENTIS PHARMA INC (US) | 2002-03-06 | — | — | EP | disclosed |
| US-5861417-A | TACHYKININ RECEPTOR ANTAGONISTS USEFUL IN TREATING ASTHMA, COUGH, BRONCHITIS, PAIN | HOECHST MARION ROUSSEL, INC. (US) | 1999-01-19 | — | — | US | disclosed |