SCHEMBL7466968

SCHEMBL7466968

Nc1ccc(CN2CCC(NC(=O)C(O)(c3ccccc3)[C@@H]3CCC(F)(F)C3)CC2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 20/20 1.00
CHRM1 P11229 20/20 1.00
CHRM3 P20309 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7461939 1.00 CHRM2 (1.00) CHRM2CHRM1CHRM3
SCHEMBL7464018 0.94 CHRM2 (1.00) CHRM2CHRM1CHRM3
SCHEMBL27502783 0.93 CHRM2 (0.87) CHRM2CHRM1CHRM3
SCHEMBL7467498 0.93 CHRM2 (0.87) CHRM2CHRM1CHRM3
SCHEMBL27520308 0.91 CHRM2 (1.00) CHRM2CHRM1CHRM3
SCHEMBL7468684 0.91 CHRM2 (1.00) CHRM2CHRM1CHRM3
SCHEMBL7464989 0.91 CHRM2 (0.82) CHRM2CHRM1CHRM3
SCHEMBL7469810 0.90 CHRM2 (1.00) CHRM2CHRM1CHRM3
SCHEMBL27520824 0.90 CHRM2 (0.88) CHRM2CHRM1CHRM3
SCHEMBL27504522 0.90 CHRM2 (1.00) CHRM2CHRM1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0930298-B1 FLUORINATED 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES BANYU PHARMA CO LTD (JP) 2002-12-18 EP claimed
CN-1226888-A Fluorinated 1,4-disubstituted piperidine derivatives BANYU PHARMA CO LTD (JP) 1999-08-25 CN claimed
EP-0930298-A1 FLUORINATED 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES BANYU PHARMACEUTICAL CO., LTD. (JP) 1999-07-21 EP claimed
CN-1226888-A Fluorinated 1,4-disubstituted piperidine derivatives BANYU PHARMA CO LTD (JP) 1999-08-25 CN disclosed