Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 18/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7555292 | 0.99 | TACR1 (0.46) | TACR1CA1CA2CA4CA9 | |
| SCHEMBL7463549 | 0.90 | TACR1 (0.51) | TACR1 | |
| Hydrochloric Acid SCHEMBL7465655 | 0.90 | TACR1 (0.51) | TACR1 | |
| SCHEMBL6133052 | 0.90 | TACR1 (0.47) | TACR1CA1CA2CA4CA9 | |
| Hydrochloric Acid SCHEMBL7463514 | 0.89 | TACR1 (0.50) | TACR1 | |
| Hydrochloric Acid SCHEMBL7472932 | 0.89 | TACR1 (0.46) | TACR1CA1CA2CA4CA9 | |
| Hydrochloric Acid SCHEMBL7460930 | 0.88 | TACR1 (0.50) | TACR1 | |
| Hydrochloric Acid SCHEMBL7460904 | 0.88 | TACR1 (0.46) | TACR1CA1CA2CA4CA9 | |
| Hydrochloric Acid SCHEMBL7460897 | 0.88 | TACR1 (0.46) | TACR1CA1CA2CA4CA9 | |
| Hydrochloric Acid SCHEMBL7467254 | 0.87 | TACR1 (0.45) | TACR1CA1CA2CA4CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0873320-B1 | PIPERAZINE DERIVATIVES AS TACHYKININ ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2002-06-12 | — | — | EP | disclosed |