Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7471261 | 0.90 | CA12 (0.49) | SMPD1HDAC8HDAC1HDAC6TSHR | |
| SCHEMBL7473893 | 0.89 | NOTUM (0.44) | MAPTSMN1; SMN2CYP2C9MAPK1LMNA | |
| SCHEMBL7473467 | 0.88 | NPC1 (0.45) | MAPTSMN1; SMN2CYP1A2CYP2C19HDAC8 | |
| SCHEMBL27478197 | 0.81 | CYSLTR1 (0.52) | MAPT | |
| SCHEMBL7471939 | 0.77 | MRGPRX4 (0.41) | SMN1; SMN2CYP1A2CYP2C9KMT2AMEN1 | |
| SCHEMBL7471233 | 0.76 | NPC1 (0.44) | MAPTSMN1; SMN2HDAC8MAPK1KMT2A | |
| SCHEMBL7471878 | 0.76 | MAPT (0.53) | MAPTSMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL7470761 | 0.74 | MAPT (0.42) | MAPTSMN1; SMN2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7466568 | 0.73 | MYC (0.45) | MAPTSMN1; SMN2NPSR1KMT2AMEN1 | |
| SCHEMBL7467175 | 0.72 | MAPT (0.44) | MAPTMAPK1LMNAKMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786457-B1 | AZOLE DERIVATIVES | YAMANOUCHI PHARMA CO LTD (JP) | 2002-05-29 | — | — | EP | disclosed |
| US-5981559-A | USEFUL IN PREVENTING OR TREATING ALLERGIC DISEASES, ISCHEMIC HEART DISEASES OR ISCHEMIC BRAIN DISEASES | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0786457-A1 | AZOLE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |