Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KIT | P10721 | 4/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.35 |
| ▸ | FLT4 | P35916 | 4/20 | 0.35 |
| ▸ | KDR | P35968 | 4/20 | 0.35 |
| ▸ | FLT3 | P36888 | 4/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.35 |
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.35 |
| ▸ | FLT1 | P17948 | 3/20 | 0.35 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.35 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.35 |
| ▸ | GEMIN4 | P57678 | 1/20 | 0.35 |
| ▸ | HSF1 | Q00613 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22734491 | 1.00 | MKNK2 (0.45) | MKNK2CA1CA9SMN1; SMN2KIT | |
| SCHEMBL7453339 | 1.00 | MKNK2 (0.45) | MKNK2CA1CA9SMN1; SMN2KIT | |
| SCHEMBL8467675 | 1.00 | MKNK2 (0.45) | MKNK2CA1CA9SMN1; SMN2KIT | |
| SCHEMBL21761590 | 0.98 | MKNK2 (0.44) | MKNK2CA1CA9SMN1; SMN2KIT | |
| SCHEMBL21761444 | 0.98 | MKNK2 (0.44) | MKNK2CA1CA9SMN1; SMN2KIT | |
| SCHEMBL19312328 | 0.98 | MKNK2 (0.44) | MKNK2CA1CA9SMN1; SMN2KIT | |
| SCHEMBL19312322 | 0.98 | MKNK2 (0.44) | MKNK2CA1CA9SMN1; SMN2KIT | |
| SCHEMBL17724028 | 0.98 | MKNK2 (0.44) | MKNK2CA1CA9SMN1; SMN2KIT | |
| SCHEMBL21761540 | 0.98 | MKNK2 (0.44) | MKNK2CA1CA9SMN1; SMN2KIT | |
| SCHEMBL24667613 | 0.93 | MKNK2 (0.43) | MKNK2CA1CA9SMN1; SMN2KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889945-B1 | FRAGRANT MACROCYCLIC LACTONES | FIRMENICH & CIE (CH) | 2002-12-04 | — | — | EP | disclosed |
| US-RE36493-E | Fragrant macrocyclic lactones | FIRMENICH SA (CH) | 2000-01-11 | — | — | US | disclosed |
| US-5792740-A | PERFUMES; MUSKY ODORS | FIRMENICH SA (CH) | 1998-08-11 | — | — | US | disclosed |