Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 4/20 | 0.30 |
| ▸ | MAOA | P21397 | 3/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL222998 | 0.82 | CHRNA7 (0.35) | HTR2AHTR2CHTR2BCHRNA7TRPA1 | |
| SCHEMBL1577842 | 0.82 | HTR2A (0.41) | HTR2AHTR2CHTR2BMAOBMAOA | |
| Hydrogen Sulfide SCHEMBL8857190 | 0.80 | CHRNA7 (0.34) | HTR2AHTR2CHTR2BCHRNA7TRPA1 | |
| SCHEMBL4794111 | 0.78 | KDM1A (0.38) | HTR2AHTR2CHTR2BCHRNA7MAOB | |
| SCHEMBL909812 | 0.78 | CHRNA7 (0.33) | HTR2AHTR2CHTR2BCHRNA7TRPA1 | |
| SCHEMBL6496498 | 0.78 | HTR2A (0.42) | HTR2AHTR2CHTR2BMAOBMAOA | |
| SCHEMBL909125 | 0.78 | CHRNA7 (0.33) | HTR2AHTR2CHTR2BCHRNA7TRPA1 | |
| SCHEMBL5390121 | 0.78 | CHRNA7 (0.33) | HTR2AHTR2CHTR2BCHRNA7TRPA1 | |
| SCHEMBL7422826 | 0.78 | HTR2A (0.38) | HTR2AHTR2CHTR2BMAOBMAOA | |
| SCHEMBL7199456 | 0.78 | CHRNA7 (0.41) | CHRNA7TRPA1CA2MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1034939-A | — | — | None | — | — | JP | disclosed |
| CN-109503686-B | Novel nucleoside phosphoramidate compounds and uses thereof | 南京圣和药业股份有限公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-108546277-B | Novel nucleoside phosphoramidate compounds and uses thereof | 南京圣和药业股份有限公司 | 2021-05-07 | — | — | CN | disclosed |
| CN-108314697-B | Novel nucleoside phosphoramidate compounds and uses thereof | 南京圣和药业股份有限公司 | 2021-05-07 | — | — | CN | disclosed |
| EP-2430012-A1 | 7-AZA-SPIRO[3.5]NONANE-7-CARBOXYLATE DERIVATIVES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-03-21 | — | — | EP | disclosed |
| WO-2011089550-A1 | ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI AVENTIS (FR) | 2011-07-28 | — | — | WO | disclosed |
| WO-2010130945-A1 | 7-AZA-SPIRO[3.5]NONANE-7-CARBOXYLATE DERIVATIVES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2010-11-18 | — | — | WO | disclosed |
| JP-S6434939-A | UNSATURATED ALKOXYFLUOROBIPHENYL | CHISSO CORP | 1989-02-06 | — | — | JP | disclosed |