Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CCNK | O75909 | 2/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | CDK7 | P50613 | 2/20 | 0.41 |
| ▸ | CCNH | P51946 | 2/20 | 0.41 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.41 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7462642 | 1.00 | MEN1 (0.41) | MEN1KMT2ANPSR1KDM4ECCNK | |
| SCHEMBL7468744 | 0.89 | CYP1A2 (0.43) | NPSR1KDM4ECCNKCCNA2CDK2 | |
| SCHEMBL7475340 | 0.89 | CYP1A2 (0.43) | NPSR1KDM4ECCNKCCNA2CDK2 | |
| SCHEMBL7468836 | 0.88 | EPHX2 (0.41) | MEN1KMT2AKDM4ECCNKCCNA2 | |
| SCHEMBL382771 | 0.87 | GAA (0.46) | MEN1KMT2ANPSR1KDM4EMAPT | |
| SCHEMBL7053339 | 0.82 | CASR (0.54) | MEN1KMT2ANPSR1KDM4ECASR | |
| SCHEMBL7463214 | 0.82 | CASR (0.54) | MEN1KMT2ANPSR1KDM4ECASR | |
| SCHEMBL7469473 | 0.82 | MAPK8 (0.39) | MEN1KMT2ANPSR1KDM4ECCNK | |
| SCHEMBL6497606 | 0.81 | KDM4E (0.54) | MEN1KMT2AKDM4ECCNKCDK12 | |
| SCHEMBL6498986 | 0.81 | KDM4E (0.54) | MEN1KMT2AKDM4ECCNKCDK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1227083-A1 | 3-AMINOPIPERIDINE DERIVATIVES AS INTEGRIN $g(a)v$g(b)3 ANTAGONISTS | MEIJI SEIKA KAISHA LTD. (JP) | 2002-07-31 | — | — | EP | disclosed |