Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 9/20 | 0.43 |
| ▸ | HRAS | P01112 | 8/20 | 0.43 |
| ▸ | ESR1 | P03372 | 8/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7472023 | 0.89 | HRAS (0.51) | ESR2HRASESR1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7466261 | 0.85 | HRAS (0.49) | ESR2HRASESR1KMT2AMEN1 | |
| SCHEMBL7478831 | 0.84 | HRAS (0.43) | ESR2HRASESR1SMN1; SMN2TP53 | |
| SCHEMBL7471663 | 0.84 | HRAS (0.46) | ESR2HRASESR1SMN1; SMN2KMT2A | |
| SCHEMBL7469237 | 0.83 | HRAS (0.45) | ESR2HRASESR1KMT2AMEN1 | |
| SCHEMBL8298671 | 0.83 | HRAS (0.46) | ESR2HRASESR1KMT2AMEN1 | |
| SCHEMBL7467693 | 0.82 | HRAS (0.47) | ESR2HRASESR1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7477283 | 0.82 | HRAS (0.50) | ESR2HRASESR1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7470484 | 0.82 | HRAS (0.47) | ESR2HRASESR1EGFRERBB2 | |
| Hydrochloric Acid SCHEMBL7471999 | 0.81 | HRAS (0.52) | ESR2HRASESR1EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711768-B1 | BENZIMIDAZOLE DERIVATIVE | MITSUI CHEMICALS INC (JP) | 2002-02-13 | — | — | EP | disclosed |
| EP-0711768-A1 | BENZIMIDAZOLE DERIVATIVE | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-15 | — | — | EP | disclosed |