Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL371245 | 0.80 | — | — | |
| SCHEMBL27737613 | 0.78 | TSHR (0.33) | TSHR | |
| Hydrochloric Acid SCHEMBL6705010 | 0.76 | TSHR (0.32) | TSHR | |
| SCHEMBL7470267 | 0.76 | TSHR (0.32) | TSHR | |
| SCHEMBL27827432 | 0.74 | TSHR (0.31) | TSHR | |
| Hydrochloric Acid SCHEMBL10697475 | 0.74 | TSHR (0.31) | TSHR | |
| SCHEMBL11319866 | 0.74 | TSHR (0.31) | TSHR | |
| SCHEMBL6772296 | 0.74 | — | — | |
| SCHEMBL11779956 | 0.71 | — | — | |
| SCHEMBL1779733 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1208102-A1 | SYNTHESIS OF SUBSTITUTED PYRAZOLOPYRIMIDINES | Neurocrine Biosciences, Inc. (US) | 2002-05-29 | — | — | EP | disclosed |
| WO-2001010868-A1 | SYNTHESIS OF SUBSTITUTED PYRAZOLOPYRIMIDINES | NEUROCRINE BIOSCIENCES, INC. (US) | 2001-02-15 | — | — | WO | disclosed |