Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | CDC25B | P30305 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CDC25A | P30304 | 1/20 | 0.43 |
| ▸ | CDC25C | P30307 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7472107 | 0.88 | TSHR (0.61) | TSHRHSD17B10ALDH1A1CDC25BKDM4E | |
| SCHEMBL3454897 | 0.85 | TSHR (0.67) | TSHRHSD17B10ALDH1A1CDC25BKDM4E | |
| SCHEMBL29003696 | 0.84 | TSHR (0.65) | TSHRHSD17B10ALDH1A1CDC25BKDM4E | |
| SCHEMBL180024 | 0.80 | TSHR (0.69) | TSHRHSD17B10ALDH1A1CDC25BKDM4E | |
| SCHEMBL29387070 | 0.80 | TSHR (0.69) | TSHRHSD17B10ALDH1A1CDC25BKDM4E | |
| SCHEMBL7296075 | 0.80 | TSHR (0.59) | TSHRHSD17B10ALDH1A1KMT2ALMNA | |
| SCHEMBL28823022 | 0.79 | TSHR (0.57) | TSHRHSD17B10ALDH1A1CDC25BKDM4E | |
| Ammonia Solution, Strong SCHEMBL10715942 | 0.79 | TSHR (0.67) | TSHRHSD17B10ALDH1A1CDC25BKDM4E | |
| SCHEMBL13059263 | 0.79 | TSHR (0.53) | TSHRHSD17B10ALDH1A1CDC25BKDM4E | |
| SCHEMBL2296422 | 0.78 | TSHR (0.61) | TSHRHSD17B10ALDH1A1CDC25BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711768-B1 | BENZIMIDAZOLE DERIVATIVE | MITSUI CHEMICALS INC (JP) | 2002-02-13 | — | — | EP | disclosed |
| US-5852011-A | Benzimidazole derivatives | MITSUI CHEMICALS, INC. (JP) | 1998-12-22 | — | — | US | disclosed |
| EP-0711768-A1 | BENZIMIDAZOLE DERIVATIVE | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-15 | — | — | EP | disclosed |