SCHEMBL7470726

SCHEMBL7470726

NC(CCC(=O)NC(CS)C(=O)NC(CCC(=O)O)C(=O)O)C(=O)O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.69
GSTK1 Q9Y2Q3 1/20 0.69
FOLH1 Q04609 4/20 0.55
NOD1 Q9Y239 8/20 0.53
GRM8 O00222 1/20 0.50
GRM6 O15303 1/20 0.50
GRIN2D O15399 1/20 0.50
GRIN3B O60391 1/20 0.50
GSR P00390 1/20 0.50
CYP1A2 P05177 1/20 0.50
GRIK1 P39086 1/20 0.50
GRM5 P41594 1/20 0.50
GRIA1 P42261 1/20 0.50
GRIA2 P42262 1/20 0.50
GRIA3 P42263 1/20 0.50
SLC1A3 P43003 1/20 0.50
SLC1A2 P43004 1/20 0.50
SLC1A1 P43005 1/20 0.50
GRIA4 P48058 1/20 0.50
GRIN1 Q05586 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7470740 1.00 PTGS1 (0.69) PTGS1GSTK1FOLH1NOD1GRM8
SCHEMBL929035 0.91 PTGS1 (0.72) PTGS1GSTK1FOLH1NOD1GRM8
SCHEMBL31744866 0.91 FOLH1 (0.59) PTGS1GSTK1FOLH1NOD1GRM8
SCHEMBL31029227 0.91 FOLH1 (0.59) PTGS1GSTK1FOLH1NOD1GRM8
SCHEMBL31029180 0.91 FOLH1 (0.59) PTGS1GSTK1FOLH1NOD1GRM8
SCHEMBL31744671 0.91 FOLH1 (0.59) PTGS1GSTK1FOLH1NOD1GRM8
SCHEMBL31744879 0.91 FOLH1 (0.59) PTGS1GSTK1FOLH1NOD1GRM8
SCHEMBL31744593 0.91 FOLH1 (0.59) PTGS1GSTK1FOLH1NOD1GRM8
SCHEMBL31744942 0.91 FOLH1 (0.59) PTGS1GSTK1FOLH1NOD1GRM8
SCHEMBL31029187 0.91 FOLH1 (0.59) PTGS1GSTK1FOLH1NOD1GRM8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116546981-A Compositions and methods using at least one glycine or derivative thereof and/or at least one N-acetylcysteine or derivative thereof and at least one thymol and/or carvacrol 雀巢产品有限公司 2023-08-04 CN claimed
CN-114214341-B Application of tomato SlSERAT1, 1 gene or fragment thereof in plant development process 山西大学 2023-12-26 CN disclosed
CN-116546981-A Compositions and methods using at least one glycine or derivative thereof and/or at least one N-acetylcysteine or derivative thereof and at least one thymol and/or carvacrol 雀巢产品有限公司 2023-08-04 CN disclosed
CN-114214341-A Application of tomato SlSERAT1, 1 gene or its fragment in plant development process 山西大学 2022-03-22 CN disclosed
US-10370675-B2 Transgenic plants exhibiting enhanced phytochelatin-based heavy metal tolerance and methods of use thereof UNITED STATES DEPARTMENT OF ENERGY 2019-08-06 US disclosed
US-20170342436-A1 TRANSGENIC PLANTS EXHIBITING ENHANCED PHYTOCHELATIN-BASED HEAVY METAL TOLERANCE AND METHODS OF USE THEREOF UNITED STATES DEPARTMENT OF ENERGY 2017-11-30 US disclosed
US-6489537-B1 ISOLATED NUCLEIC ACID ENCODING A PHYTOCHELATIN SYNTHASE; TRANSGENIC PLANTS WITH HEAVY METAL RESISTANCE; GROUNDWATER PURIFICATION OF HEAVY METALS THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA 2002-12-03 US disclosed
EP-1179055-A1 NOVEL PHYTOCHELATIN SYNTHASES AND USES THEREFOR THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2002-02-13 EP disclosed
WO-2000071695-A1 NOVEL PHYTOCHELATIN SYNTHASES AND USES THEREFOR THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2000-11-30 WO disclosed