Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 9/20 | 0.71 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.71 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7482442 | 0.83 | F10 (1.00) | F10PRSS1KMT2AALDH1A1LMNA | |
| SCHEMBL7475462 | 0.83 | F10 (0.81) | F10PRSS1MEN1KMT2AALDH1A1 | |
| SCHEMBL7473566 | 0.81 | F10 (1.00) | F10PRSS1 | |
| SCHEMBL7477445 | 0.81 | F10 (0.71) | F10PRSS1MEN1KMT2ALMNA | |
| SCHEMBL7475469 | 0.80 | F10 (0.61) | F10PRSS1MEN1KMT2AALDH1A1 | |
| SCHEMBL7472609 | 0.80 | F10 (0.72) | F10PRSS1MEN1KMT2AALDH1A1 | |
| SCHEMBL7475555 | 0.76 | F10 (0.82) | F10PRSS1 | |
| SCHEMBL29131991 | 0.72 | NAMPT (0.68) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL14426996 | 0.71 | FFAR1 (0.54) | F10PRSS1MEN1KMT2AALDH1A1 | |
| SCHEMBL4293548 | 0.71 | MEN1 (0.74) | MEN1KMT2AALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1183235-A2 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS, INC. (US) | 2002-03-06 | — | — | EP | disclosed |
| WO-2000071510-A2 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS, INC. (US) | 2000-11-30 | — | — | WO | disclosed |