Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 20/20 | 0.49 |
| ▸ | TACR1 | P25103 | 2/20 | 0.47 |
| ▸ | TACR2 | P21452 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7474421 | 0.94 | HRH1 (0.52) | HRH1TACR1TACR2 | |
| SCHEMBL7491746 | 0.89 | KCNH2 (0.45) | HRH1TACR1TACR2 | |
| SCHEMBL7464918 | 0.89 | HRH1 (0.58) | HRH1TACR2 | |
| SCHEMBL7473738 | 0.88 | HRH1 (0.47) | HRH1TACR2 | |
| SCHEMBL7472517 | 0.87 | HRH1 (0.52) | HRH1 | |
| SCHEMBL7468505 | 0.87 | TACR2 (0.47) | HRH1TACR2 | |
| SCHEMBL7473947 | 0.86 | HRH1 (0.58) | HRH1TACR1 | |
| SCHEMBL7473282 | 0.85 | TACR2 (0.59) | TACR2 | |
| SCHEMBL7472794 | 0.85 | HRH1 (0.60) | HRH1TACR1TACR2 | |
| SCHEMBL7470780 | 0.85 | HRH1 (0.47) | HRH1TACR1TACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882038-B1 | SUBSTITUTED N-METHYL-N-(4-(PIPERIDIN-1-YL)-2-(ARYL)BUTYL)BENZAMIDES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | AVENTIS PHARMA INC (US) | 2002-12-18 | — | — | EP | disclosed |
| US-6297259-B1 | HISTAMINE RECEPTOR ANTAGONISTS AND TACHYKININ RECEPTOR ANTAGONISTS. | AVENTIS PHARMACEUTICALS INC. | 2001-10-02 | — | — | US | disclosed |
| US-5998439-A | RESPIRATORY SYSTEM DISORDERS | Hoescht Marion Roussel, Inc. (US) | 1999-12-07 | — | — | US | disclosed |