Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7471879 | 1.00 | KMT2A (0.45) | KMT2AMEN1RECQLLMNAMAPT | |
| SCHEMBL7471887 | 1.00 | KMT2A (0.45) | KMT2AMEN1RECQLLMNAMAPT | |
| SCHEMBL7377043 | 0.85 | RECQL (0.53) | KMT2AMEN1RECQLMAPTNR1I2 | |
| SCHEMBL7431926 | 0.85 | RECQL (0.53) | KMT2AMEN1RECQLMAPTNR1I2 | |
| SCHEMBL7377051 | 0.85 | RECQL (0.53) | KMT2AMEN1RECQLMAPTNR1I2 | |
| SCHEMBL18172999 | 0.82 | RECQL (0.50) | KMT2AMEN1RECQLLMNAMAPT | |
| SCHEMBL18173002 | 0.82 | RECQL (0.50) | KMT2AMEN1RECQLLMNAMAPT | |
| SCHEMBL18172997 | 0.82 | RECQL (0.50) | KMT2AMEN1RECQLLMNAMAPT | |
| SCHEMBL1914725 | 0.82 | MEN1 (0.44) | KMT2AMEN1RECQLLMNAMAPT | |
| SCHEMBL1915838 | 0.80 | RECQL (0.69) | KMT2AMEN1RECQLMAPTNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889879-B1 | BUTADIENE DERIVATIVES AND PROCESS FOR PREPARING THEREOF | TANABE SEIYAKU CO (JP) | 2002-06-12 | — | — | EP | disclosed |
| US-6248743-B1 | ANTITHROMBOTIC AGENTS EFFECTIVE TO INHIBIT THE PRODUCTION OF TYPE 1 PLASMINOGEN ACTIVATOR INHIBITOR (PAI-1) | TANABE SEIYAKU CO., LTD. (JP) | 2001-06-19 | — | — | US | disclosed |