SCHEMBL74720

SCHEMBL74720

COc1ccc2[nH]ccc2c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.71
KMT2A Q03164 3/20 0.71
POLB P06746 1/20 0.71
MAPK1 P28482 1/20 0.71
MAOA P21397 2/20 0.58
MAOB P27338 1/20 0.58
AXL P30530 1/20 0.53
AHR P35869 3/20 0.50
NR4A2 P43354 2/20 0.50
CYP2A6 P11509 2/20 0.50
LTA4H P09960 2/20 0.50
KDM4E B2RXH2 2/20 0.50
MAPT P10636 2/20 0.50
F7 P08709 1/20 0.50
F3 P13726 1/20 0.50
USP2 O75604 1/20 0.50
GAA P10253 1/20 0.50
ALOX15 P16050 1/20 0.50
RAD51 Q06609 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29992449 1.00 MEN1 (0.71) MEN1KMT2APOLBMAPK1MAOA
Hydrochloric Acid SCHEMBL27528155 0.98 MEN1 (0.69) MEN1KMT2APOLBMAPK1MAOA
Ammonia Solution, Strong SCHEMBL28589598 0.98 MEN1 (0.69) MEN1KMT2APOLBMAPK1MAOA
Benzene SCHEMBL28261496 0.93 MEN1 (0.62) MEN1KMT2APOLBMAPK1MAOA
Indole SCHEMBL28308971 0.91 MEN1 (0.66) MEN1KMT2APOLBMAPK1MAOA
Acetic Acid SCHEMBL27184854 0.89 POLB (0.59) MEN1KMT2APOLBMAPK1MAOA
SCHEMBL28344875 0.89 AHR (0.70) MEN1KMT2APOLBMAPK1MAOA
Biphenyl SCHEMBL27962650 0.89 NPC1 (0.64) MEN1KMT2APOLBMAPK1MAOA
SCHEMBL8868277 0.89 MEN1 (0.58) MEN1KMT2APOLBMAPK1MAOA
SCHEMBL13548685 0.88 MEN1 (0.57) MEN1KMT2APOLBMAPK1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2551 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4679087-A1 BIOMARKER AND USE THEREOF MEIJI CO., LTD (JP) 2026-01-14 EP claimed
CN-120058668-A Mitochondrial fluorescent probe independent of mitochondrial membrane potential and preparation method and application thereof 中国科学院深圳先进技术研究院 2025-05-30 CN claimed
CN-120058669-A Autophagy regulator and preparation method and application thereof 中国科学院深圳先进技术研究院 2025-05-30 CN claimed
CN-119857098-A Application of indole triazole derivative in preparation of drug-resistant candida albicans drug 云南中医药大学 2025-04-22 CN claimed
CN-119613319-A Compositions comprising benzoates of 5-methoxy-N, N-dimethyltryptamine 贝克利心理科技有限公司 2025-03-14 CN claimed
CN-116375627-B Preparation method of melatonin 南京神奇科技开发有限公司 2025-03-11 CN claimed
US-20240327346-A1 METHOD FOR PREPARING A TRYPTAMINE DERIVATIVE GH Research Ireland Limited (IE) 2024-10-03 US claimed
WO-2024190663-A1 BIOMARKER AND USE THEREOF 株式会社明治 2024-09-19 WO claimed
CN-118437307-A Application of amorphous carbon material and synthetic method of poly-deuterated aromatic compound 无锡绿能电合科技有限公司 2024-08-06 CN claimed
CN-118355909-A Application of 5-methoxyindole in preventing and controlling plant nematodes 南京农业大学 2024-07-19 CN claimed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed
EP-0673782-A2 Recording sheets containing pyrrole, pyrrolidine, pyridine, piperidine, homopiperidine, quinoline, isoquinoline, quinuclidine, indole, and indazole compounds XEROX CORPORATION (US) 1995-09-27 EP claimed
US-4405718-A Method and composition for urobilinogen control standard MILES LABORATORIES, INC. (US) 1983-09-20 US claimed
EP-0009445-B1 PROCESS FOR THE PREPARATION OF 9-HYDROXY-ELLIPTICINE AND DERIVATIVES THEREOF ANVAR Agence Nationale de Valorisation de la Recherche (FR) 1983-05-18 EP claimed
EP-0071766-A1 Process and composition for urobilinogen control standard MILES LABORATORIES, INC. (US) 1983-02-16 EP claimed
US-4360594-A REACTING INDOLE COMPOUND WITH SERINE, OR WITH PYRUVIC ACID AND AMMONIUM ION ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1982-11-23 US claimed
US-4349627-A Process for producing L-tryptophan or derivatives thereof using a microorganism ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1982-09-14 US claimed
US-4013404-A Method of dyeing hair with indolines, indoles and indazoles AMERICAN CYANAMID COMPANY (US) 1977-03-22 US claimed