Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28287261 | 0.91 | KMT2A (0.63) | KMT2ASMN1; SMN2ALDH1A1EPHX2MEN1 | |
| SCHEMBL19169564 | 0.85 | SMN1; SMN2 (0.68) | KMT2ASMN1; SMN2ALDH1A1EPHX2MEN1 | |
| SCHEMBL9341104 | 0.85 | KMT2A (0.83) | KMT2ASMN1; SMN2ALDH1A1EPHX2MEN1 | |
| SCHEMBL31658991 | 0.85 | KMT2A (0.83) | KMT2ASMN1; SMN2ALDH1A1EPHX2MEN1 | |
| SCHEMBL7476974 | 0.84 | KMT2A (0.58) | KMT2ASMN1; SMN2ALDH1A1EPHX2MEN1 | |
| SCHEMBL3715361 | 0.82 | KMT2A (0.69) | KMT2ASMN1; SMN2ALDH1A1EPHX2MEN1 | |
| SCHEMBL30131390 | 0.82 | KMT2A (0.69) | KMT2ASMN1; SMN2ALDH1A1EPHX2MEN1 | |
| SCHEMBL3673650 | 0.82 | KMT2A (0.73) | KMT2ASMN1; SMN2ALDH1A1EPHX2MEN1 | |
| SCHEMBL8516755 | 0.82 | SMN1; SMN2 (0.90) | KMT2ASMN1; SMN2ALDH1A1EPHX2MEN1 | |
| SCHEMBL10706270 | 0.81 | KMT2A (0.71) | KMT2ASMN1; SMN2ALDH1A1EPHX2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861077-B1 | HEMOREGULATORY COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2002-02-06 | — | — | EP | claimed |
| EP-0861077-A4 | HEMOREGULATORY COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 1999-03-03 | — | — | EP | claimed |
| EP-0861077-A1 | HEMOREGULATORY COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-09-02 | — | — | EP | claimed |
| WO-1997017964-A1 | HEMOREGULATORY COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-05-22 | — | — | WO | claimed |
| EP-1189901-A1 | OXAZAHETEROCYCLES AS PROTEASE INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2002-03-27 | — | — | EP | disclosed |
| EP-0861077-B1 | HEMOREGULATORY COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2002-02-06 | — | — | EP | disclosed |
| WO-2000073302-A1 | OXAZAHETEROCYCLES AS PROTEASE INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2000-12-07 | — | — | WO | disclosed |
| US-6107309-A | BLOOD DISORDERS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-08-22 | — | — | US | disclosed |
| EP-0861077-A4 | HEMOREGULATORY COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 1999-03-03 | — | — | EP | disclosed |
| EP-0861077-A1 | HEMOREGULATORY COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-09-02 | — | — | EP | disclosed |
| WO-1997017964-A1 | HEMOREGULATORY COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-05-22 | — | — | WO | disclosed |