Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7473281 | 0.86 | MEN1 (0.38) | PARP1TSHRKMT2AMEN1MAPK1 | |
| SCHEMBL7468831 | 0.85 | USP2 (0.42) | TSHRKMT2AMEN1HSD17B10GAA | |
| SCHEMBL7470594 | 0.85 | USP2 (0.53) | MAPTTHRBTSHRALDH1A1KMT2A | |
| SCHEMBL8601457 | 0.84 | USP2 (0.39) | TP53TSHRKMT2AMEN1MAPK1 | |
| SCHEMBL7463472 | 0.84 | HSD17B10 (0.48) | PARP1TP53MAPTTSHRALDH1A1 | |
| SCHEMBL7468492 | 0.84 | BRD4 (0.39) | TP53ALDH1A1KMT2AMEN1GAA | |
| SCHEMBL7478473 | 0.83 | KMT2A (0.42) | MAPTALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL7475258 | 0.83 | HSD17B10 (0.44) | MAPTTSHRALDH1A1KMT2AMEN1 | |
| SCHEMBL7469532 | 0.83 | TP53 (0.30) | TP53KMT2AMEN1 | |
| SCHEMBL7464320 | 0.82 | USP2 (0.38) | MAPTTSHRKMT2AMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-B1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO MCNEIL PHARM INC (US) | 2002-12-18 | — | — | EP | disclosed |
| US-5854242-A | Benzoxazine antimicrobial agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-12-29 | — | — | US | disclosed |
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| US-5696117-A | BACTERICIDE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-12-09 | — | — | US | disclosed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |