Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18287858 | 0.95 | TSHR (0.57) | TSHRKMT2AGAACHRNA7HTR3E | |
| SCHEMBL9244017 | 0.94 | TSHR (0.65) | TSHRKMT2AGAACHRNA7HTR3E | |
| SCHEMBL7480885 | 0.92 | TSHR (0.62) | TSHRKMT2AGAACHRNA7HTR3E | |
| SCHEMBL5340974 | 0.87 | TSHR (0.47) | TSHRKMT2AGAACHRNA7HTR3E | |
| SCHEMBL7477597 | 0.87 | TSHR (0.52) | TSHRKMT2AGAACHRNA7HTR3E | |
| SCHEMBL17931093 | 0.86 | TSHR (0.56) | TSHRKMT2AGAACHRNA7HTR3E | |
| SCHEMBL20250945 | 0.86 | TSHR (0.48) | TSHRKMT2AGAACYP2D6ALDH1A1 | |
| SCHEMBL4804356 | 0.84 | TSHR (0.57) | TSHRKMT2AGAACHRNA7HTR3E | |
| SCHEMBL13474844 | 0.84 | KMT2A (0.61) | TSHRKMT2AGAACYP2D6ALDH1A1 | |
| SCHEMBL19937304 | 0.84 | KMT2A (0.61) | TSHRKMT2AGAACYP2D6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0309402-B2 | N-substituted hindered amine stabilizers | CIBA SC HOLDING AG (CH) | 2002-06-12 | — | — | EP | disclosed |
| EP-0309402-B1 | N-substituted hindered amine stabilizers | CIBA GEIGY AG (CH) | 1995-01-11 | — | — | EP | disclosed |
| US-5204473-A | O-substituted N-hydroxy hindered amine stabilizers | CIBA-GEIGY CORPORATION (US) | 1993-04-20 | — | — | US | disclosed |
| US-4921962-A | REACTION OF AMINE WITH HYDROPEROXIDE | CIBA-GEIGY CORPORATION (US) | 1990-05-01 | — | — | US | disclosed |
| EP-0309402-A1 | N-substituted hindered amine stabilizers | CIBA-GEIGY AG (CH) | 1989-03-29 | — | — | EP | disclosed |