SCHEMBL7474073

SCHEMBL7474073

CCCCCCCCCOc1ccc(Br)cc1

nearest known ligand 0.66

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NR5A1 Q13285 1/20 0.66
LTA4H P09960 4/20 0.58
TP53 P04637 2/20 0.58
TSHR P16473 1/20 0.58
PLA2G4B P0C869 3/20 0.56
RARB P10826 3/20 0.53
NPC1 O15118 1/20 0.53
LMNA P02545 1/20 0.53
GAA P10253 1/20 0.53
MAPT P10636 1/20 0.53
ALOX15 P16050 1/20 0.53
RAB9A P51151 1/20 0.53
HSD17B10 Q99714 1/20 0.53
DRD2 P14416 1/20 0.51
DRD4 P21917 1/20 0.51
DRD3 P35462 1/20 0.51
PLA2G4A P47712 1/20 0.50
ATM Q13315 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5599235 1.00 NR5A1 (0.66) NR5A1LTA4HTP53TSHRPLA2G4B
SCHEMBL8215140 1.00 NR5A1 (0.66) NR5A1LTA4HTP53TSHRPLA2G4B
SCHEMBL917535 1.00 NR5A1 (0.66) NR5A1LTA4HTP53TSHRPLA2G4B
SCHEMBL6740617 1.00 NR5A1 (0.66) NR5A1LTA4HTP53TSHRPLA2G4B
SCHEMBL4800857 1.00 NR5A1 (0.66) NR5A1LTA4HTP53TSHRPLA2G4B
SCHEMBL917687 1.00 NR5A1 (0.66) NR5A1LTA4HTP53TSHRPLA2G4B
SCHEMBL8216305 1.00 NR5A1 (0.66) NR5A1LTA4HTP53TSHRPLA2G4B
SCHEMBL1102341 1.00 NR5A1 (0.66) NR5A1LTA4HTP53TSHRPLA2G4B
SCHEMBL917938 0.98 NR5A1 (0.62) NR5A1LTA4HTP53TSHRPLA2G4B
SCHEMBL7697448 0.94 RARB (0.61) NR5A1LTA4HTP53TSHRPLA2G4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1214306-A1 LIQUID CRYSTAL COMPOUNDS Qinetiq Limited (GB) 2002-06-19 EP disclosed
WO-2001021606-A1 LIQUID CRYSTAL COMPOUNDS QINETIQ LIMITED (GB) 2001-03-29 WO disclosed
EP-0767772-B1 NOVEL CHIRAL CYCLOHEXYL COMPOUNDS SECR DEFENCE (GB) 2000-08-30 EP disclosed
US-5853613-A Chiral cyclohexyl compounds SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) 1998-12-29 US disclosed
US-5683623-A FERROELECTRIC LIQUID CRYSTALS CELLS AND DEVICES FOR ELECTROOPTICAL APPARATUS CENTRAL RESEARCH LABORATORIES LIMITED (GB) 1997-11-04 US disclosed
EP-0767772-A1 NOVEL CHIRAL CYCLOHEXYL COMPOUNDS THE SECRETARY OF STATE FOR DEFENCE (GB) 1997-04-16 EP disclosed
EP-0662114-B1 DIOXANE DERIVATIVES CENTRAL RESEARCH LAB LTD (GB) 1997-02-19 EP disclosed
WO-1996000710-A1 NOVEL CHIRAL CYCLOHEXYL COMPOUNDS THE SECRETARY OF STATE FOR DEFENCE (GB) 1996-01-11 WO disclosed
EP-0662114-A1 DIOXANE DERIVATIVES. CENTRAL RESEARCH LAB LTD (GB) 1995-07-12 EP disclosed
WO-1994006885-A1 DIOXANE DERIVATIVES CENTRAL RESEARCH LABORATORIES LIMITED (GB) 1994-03-31 WO disclosed