Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 19/20 | 0.62 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7489214 | 0.92 | P2RY12 (0.63) | P2RY12USP28 | |
| SCHEMBL7002344 | 0.92 | P2RY12 (0.72) | P2RY12USP28 | |
| SCHEMBL13768794 | 0.87 | P2RY12 (0.57) | P2RY12USP28 | |
| SCHEMBL7515643 | 0.85 | P2RY12 (0.73) | P2RY12USP28 | |
| SCHEMBL7507775 | 0.84 | P2RY12 (0.73) | P2RY12USP28 | |
| SCHEMBL7003996 | 0.83 | P2RY12 (0.61) | P2RY12USP28 | |
| SCHEMBL13764368 | 0.82 | P2RY12 (0.53) | P2RY12USP28 | |
| SCHEMBL7510370 | 0.82 | P2RY12 (0.64) | P2RY12USP28 | |
| SCHEMBL7516295 | 0.81 | P2RY12 (0.64) | P2RY12USP28 | |
| SCHEMBL7996482 | 0.81 | P2RY12 (0.64) | P2RY12USP28 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0996620-B1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2002-04-17 | — | — | EP | disclosed |
| US-6156756-A | Triazolo [4,5-d]pyrimidine compounds, their use as medicaments, compositions containing them and processes for their preparation | ASTRAZENECA UK LIMITED (GB) | 2000-12-05 | — | — | US | disclosed |