Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7470970 | 0.95 | HRH1 (0.49) | HRH1TACR1 | |
| SCHEMBL7472958 | 0.93 | TACR2 (0.50) | HRH1 | |
| SCHEMBL7468717 | 0.91 | TACR2 (0.47) | HRH1TACR1 | |
| SCHEMBL7478440 | 0.91 | HRH1 (0.62) | HRH1TACR1 | |
| SCHEMBL7463581 | 0.90 | HRH1 (0.50) | HRH1TACR1 | |
| SCHEMBL7471439 | 0.89 | HRH1 (0.49) | HRH1TACR1 | |
| SCHEMBL7465947 | 0.89 | HRH1 (0.53) | HRH1TACR1 | |
| SCHEMBL7470968 | 0.88 | HRH1 (0.50) | HRH1 | |
| SCHEMBL7469129 | 0.88 | HRH1 (0.51) | HRH1TACR1 | |
| SCHEMBL7469154 | 0.87 | HRH1 (0.62) | HRH1TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882038-B1 | SUBSTITUTED N-METHYL-N-(4-(PIPERIDIN-1-YL)-2-(ARYL)BUTYL)BENZAMIDES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | AVENTIS PHARMA INC (US) | 2002-12-18 | — | — | EP | disclosed |
| US-6297259-B1 | HISTAMINE RECEPTOR ANTAGONISTS AND TACHYKININ RECEPTOR ANTAGONISTS. | AVENTIS PHARMACEUTICALS INC. | 2001-10-02 | — | — | US | disclosed |
| US-5998439-A | RESPIRATORY SYSTEM DISORDERS | Hoescht Marion Roussel, Inc. (US) | 1999-12-07 | — | — | US | disclosed |