Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 18/20 | 0.60 |
| ▸ | PDE4B | Q07343 | 17/20 | 0.60 |
| ▸ | PDE4A | P27815 | 16/20 | 0.60 |
| ▸ | PDE4C | Q08493 | 16/20 | 0.60 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7425565 | 0.91 | PDE4D (0.59) | PDE4DPDE4BPDE4APDE4CGFER | |
| SCHEMBL6943421 | 0.75 | PDE4D (0.69) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL1552878 | 0.75 | PDE4D (0.86) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL1553543 | 0.75 | PDE4D (1.00) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL1553355 | 0.75 | PDE4D (1.00) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL720382 | 0.73 | PDE4D (0.62) | PDE4DPDE4BPDE4APDE4CGFER | |
| SCHEMBL4126031 | 0.73 | PDE4D (0.61) | PDE4DPDE4BPDE4APDE4CGFER | |
| SCHEMBL5723082 | 0.71 | PDE4D (0.53) | PDE4DPDE4BPDE4APDE4CGFER | |
| SCHEMBL6836687 | 0.71 | PDE4D (0.62) | PDE4DPDE4BPDE4APDE4CGFER | |
| SCHEMBL6833314 | 0.71 | PDE4D (0.62) | PDE4DPDE4BPDE4APDE4CGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995004046-A1 | COMPOUNDS AS PDE IV AND TNF INHIBITORS | RHONE-POULENC RORER LIMITED (GB) | 1995-02-09 | — | — | WO | disclosed |