SCHEMBL747488

SCHEMBL747488

CCC=C(C)C(=O)O.CCN(CC)CC

nearest known ligand 0.34

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 1/20 0.34
GRIK2 Q13002 1/20 0.34
CHRM2 P08172 1/20 0.33
CHRM4 P08173 1/20 0.33
CHRM5 P08912 1/20 0.33
CHRM1 P11229 1/20 0.33
CHRM3 P20309 1/20 0.33
TRPA1 O75762 1/20 0.32
CD81 P60033 1/20 0.31
ALDH1A1 P00352 1/20 0.31
PTGS1 P23219 1/20 0.30
AKR1C3 P42330 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1734923 0.98 GRIK1 (0.33) GRIK1GRIK2CHRM2CHRM4CHRM5
Hydrochloric Acid SCHEMBL1734925 0.98 GRIK1 (0.33) GRIK1GRIK2CHRM2CHRM4CHRM5
SCHEMBL5716965 0.88
SCHEMBL17817 0.88
SCHEMBL17819 0.88
N,N-Dimethylethanaminium SCHEMBL11902177 0.86 GRIK1 (0.34) GRIK1GRIK2CHRM2CHRM4CHRM5
N,N-Dimethylethanaminium SCHEMBL11902174 0.86 GRIK1 (0.34) GRIK1GRIK2CHRM2CHRM4CHRM5
Trimethylammonium SCHEMBL679439 0.86 GRIK1 (0.36) GRIK1GRIK2CD81ALDH1A1PTGS1
Trimethylammonium SCHEMBL1469277 0.86 GRIK1 (0.36) GRIK1GRIK2CD81ALDH1A1PTGS1
Water SCHEMBL11376129 0.85

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2429478-A1 DENTAL ADHESIVE COMPOSITION COMPRISING ADHESION PROMOTING POLYMER ADDITIVE AND METHOD 3M Innovative Properties Company (US) 2012-03-21 EP disclosed
WO-2010132270-A1 DENTAL ADHESIVE COMPOSITION COMPRISING ADHESION PROMOTING POLYMER ADDITIVE AND METHOD 3M INNOVATIVE PROPERTIES COMPANY (US) 2010-11-18 WO disclosed