Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 14/20 | 0.43 |
| ▸ | FNTB | P49356 | 14/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7537460 | 0.99 | FNTA (0.43) | FNTAFNTBCYP11B1CYP11B2CYP19A1 | |
| SCHEMBL7477935 | 0.82 | FNTA (0.48) | FNTAFNTBCYP11B1CYP11B2CYP19A1 | |
| SCHEMBL7536078 | 0.80 | FNTA (0.45) | FNTAFNTBCYP11B1CYP11B2PGGT1B | |
| SCHEMBL7533619 | 0.80 | FNTA (0.51) | FNTAFNTBPGGT1B | |
| SCHEMBL7533109 | 0.79 | FNTA (0.45) | FNTAFNTBCYP11B1CYP11B2PGGT1B | |
| SCHEMBL7474431 | 0.79 | FNTA (0.43) | FNTAFNTBCYP11B1CYP11B2CYP19A1 | |
| SCHEMBL7540069 | 0.77 | FNTA (0.52) | FNTAFNTBPGGT1B | |
| SCHEMBL7536083 | 0.74 | FNTA (0.48) | FNTAFNTBCYP11B1CYP11B2PGGT1B | |
| Trifluoroacetic Acid SCHEMBL7533034 | 0.71 | FNTA (0.48) | FNTAFNTBCYP11B1CYP11B2PGGT1B | |
| SCHEMBL7535019 | 0.70 | FNTA (0.40) | FNTAFNTBCYP11B1CYP11B2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1045844-A4 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 2002-08-21 | — | — | EP | disclosed |
| EP-1045844-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 2000-10-25 | — | — | EP | disclosed |
| WO-1999028314-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1999-06-10 | — | — | WO | disclosed |