⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19148588 | 0.76 | — | — | |
| SCHEMBL7484367 | 0.75 | — | — | |
| SCHEMBL23868128 | 0.71 | — | — | |
| SCHEMBL25805780 | 0.71 | — | — | |
| SCHEMBL23042930 | 0.68 | — | — | |
| SCHEMBL19880227 | 0.64 | — | — | |
| SCHEMBL18756838 | 0.63 | — | — | |
| SCHEMBL13211621 | 0.62 | TDP1 (0.36) | — | |
| SCHEMBL25922078 | 0.62 | — | — | |
| SCHEMBL8859454 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109195578-A | Use of phosphorothioate derivatives as skin depigmenting agents | 比扬药妆品有限公司 | 2019-01-11 | — | — | CN | disclosed |
| EP-3243530-A1 | INTEGRIN RECEPTOR ANTAGONISTS AND THEIR USE | Allegro Pharmaceuticals, Inc. (US) | 2017-11-15 | — | — | EP | disclosed |
| WO-2017108282-A1 | BICYCLIC HYDROXAMIC ACIDS USEFUL AS INHIBITORS OF MAMMALIAN HISTONE DEACETYLASE ACTIVITY | KANCERA AB (SE) | 2017-06-29 | — | — | WO | disclosed |
| EP-0818512-B1 | Quinoline derivative and use of same | MITSUI CHEMICALS INC (JP) | 2002-10-02 | — | — | EP | disclosed |
| US-6407242-B1 | REACTING A PHTHALIMIDE COMPOUND WITH A QUINOLINE COMPOUND;ELECTROLUMINESCENCE | MITSUI CHEMICALS, INC. (JP) | 2002-06-18 | — | — | US | disclosed |
| US-6132640-A | ZINC COMPLEXES OF QUINOLINE | MITSUI CHEMICALS, INC. (JP) | 2000-10-17 | — | — | US | disclosed |
| EP-0818512-A1 | Quinoline derivative and use of same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1998-01-14 | — | — | EP | disclosed |