Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7479931 | 0.85 | HTR1D (1.00) | HTR1DHTR1B | |
| SCHEMBL7480186 | 0.85 | HTR1D (1.00) | HTR1DHTR1B | |
| SCHEMBL4342340 | 0.82 | HTR1D (1.00) | HTR1DHTR1B | |
| SCHEMBL4579705 | 0.81 | HTR1D (1.00) | HTR1DHTR1B | |
| SCHEMBL8101825 | 0.79 | HTR1D (0.80) | HTR1DHTR1B | |
| SCHEMBL8662011 | 0.79 | HTR1D (0.82) | HTR1DHTR1B | |
| SCHEMBL8984359 | 0.79 | HTR1D (1.00) | HTR1DHTR1B | |
| SCHEMBL8657524 | 0.78 | HTR1D (1.00) | HTR1DHTR1B | |
| SCHEMBL8659040 | 0.77 | HTR1D (0.76) | HTR1DHTR1B | |
| SCHEMBL7476140 | 0.77 | HTR1D (0.85) | HTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0925302-B1 | PALLADIUM CATALYZED INDOLIZATION | MERCK & CO INC (US) | 2002-11-20 | — | — | EP | claimed |
| EP-0925302-B1 | PALLADIUM CATALYZED INDOLIZATION | MERCK & CO INC (US) | 2002-11-20 | — | — | EP | disclosed |
| US-5854268-A | Azetidine, pyrrolidine and piperidine derivatives | MERCK SHARP & DOHME, LTD. (GB) | 1998-12-29 | — | — | US | disclosed |
| EP-0804434-A1 | AZETIDINE, PYRROLIDINE AND PIPERIDINE DERIVATIVES | MERCK SHARP & DOHME LTD. (GB) | 1997-11-05 | — | — | EP | disclosed |
| WO-1996004274-A1 | AZETIDINE, PYRROLIDINE AND PIPERIDINE DERIVATIVES | MERCK SHARP & DOHME LIMITED (GB) | 1996-02-15 | — | — | WO | disclosed |