Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 6/20 | 0.53 |
| ▸ | CYSLTR1 | Q9Y271 | 6/20 | 0.51 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9637029 | 0.78 | GPBAR1 (0.69) | ALOX5APCYSLTR1GPBAR1CYP1A2KDM4E | |
| SCHEMBL7454590 | 0.77 | GPBAR1 (0.74) | CYSLTR1GPBAR1CYP1A2KDM4EMEN1 | |
| SCHEMBL7480676 | 0.76 | CYSLTR1 (0.51) | ALOX5APCYSLTR1GPBAR1CYP1A2KDM4E | |
| SCHEMBL6090484 | 0.76 | CYSLTR1 (0.73) | CYSLTR1GPBAR1CYP1A2KDM4EMEN1 | |
| SCHEMBL7714863 | 0.76 | CYSLTR1 (0.66) | CYSLTR1GPBAR1CYP1A2KDM4EMEN1 | |
| SCHEMBL10533345 | 0.75 | CYSLTR1 (0.62) | CYSLTR1GPBAR1CYP1A2KDM4EMEN1 | |
| SCHEMBL9141677 | 0.75 | PPARD (0.66) | ALOX5APCYSLTR1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9207903 | 0.74 | ALOX5AP (0.58) | ALOX5APCYSLTR1GPBAR1ALDH1A1LMNA | |
| SCHEMBL7714576 | 0.74 | CYSLTR1 (0.64) | CYSLTR1GPBAR1CYP1A2KDM4EMEN1 | |
| SCHEMBL3296677 | 0.73 | CYSLTR1 (0.69) | CYSLTR1GPBAR1CYP1A2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1210343-A2 | BENZOIC ACID DERIVATIVES AND THEIR USE AS PPAR RECEPTOR AGONISTS | AstraZeneca AB (SE) | 2002-06-05 | — | — | EP | disclosed |
| WO-2001012187-A2 | BENZOIC ACID DERIVATIVES AND THEIR USE AS PPAR RECEPTOR AGONISTS | ASTRAZENECA AB (SE) | 2001-02-22 | — | — | WO | disclosed |