Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4352268 | 1.00 | HTR1D (1.00) | HTR1DHTR1B | |
| SCHEMBL4340558 | 1.00 | HTR1D (1.00) | HTR1DHTR1B | |
| SCHEMBL4579876 | 0.92 | HTR1D (1.00) | HTR1DHTR1B | |
| SCHEMBL4579883 | 0.92 | HTR1D (1.00) | HTR1DHTR1B | |
| SCHEMBL4579880 | 0.92 | HTR1D (1.00) | HTR1DHTR1B | |
| SCHEMBL4344021 | 0.91 | HTR1D (1.00) | HTR1DHTR1B | |
| SCHEMBL4577573 | 0.91 | HTR1D (1.00) | HTR1DHTR1B | |
| SCHEMBL4355208 | 0.91 | HTR1D (1.00) | HTR1DHTR1B | |
| SCHEMBL4578276 | 0.91 | HTR1D (1.00) | HTR1DHTR1B | |
| SCHEMBL7474266 | 0.91 | HTR1D (1.00) | HTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0925302-B1 | PALLADIUM CATALYZED INDOLIZATION | MERCK & CO INC (US) | 2002-11-20 | — | — | EP | claimed |
| US-5854268-A | Azetidine, pyrrolidine and piperidine derivatives | MERCK SHARP & DOHME, LTD. (GB) | 1998-12-29 | — | — | US | claimed |
| EP-0925302-B1 | PALLADIUM CATALYZED INDOLIZATION | MERCK & CO INC (US) | 2002-11-20 | — | — | EP | disclosed |
| US-5854268-A | Azetidine, pyrrolidine and piperidine derivatives | MERCK SHARP & DOHME, LTD. (GB) | 1998-12-29 | — | — | US | disclosed |