Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | REN | P00797 | 3/20 | 0.31 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.31 |
| ▸ | MAP1LC3A | Q9H492 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7482086 | 0.89 | GAA (0.35) | BRD4MAP1LC3BMAP1LC3ACYP3A4 | |
| SCHEMBL6174348 | 0.84 | MAPK1 (0.34) | RENCYP3A4 | |
| SCHEMBL7400236 | 0.82 | TRIM24 (0.39) | — | |
| SCHEMBL7397144 | 0.81 | PDE4B (0.40) | BRD4CYP3A4 | |
| SCHEMBL6174251 | 0.81 | CYP2C9 (0.38) | RENCYP3A4 | |
| SCHEMBL7487811 | 0.80 | ADRB3 (0.33) | MAP1LC3BMAP1LC3A | |
| SCHEMBL6174752 | 0.79 | NQO1 (0.35) | RENCYP3A4 | |
| SCHEMBL7405143 | 0.79 | HSD17B2 (0.39) | BRD4 | |
| SCHEMBL7396533 | 0.79 | KDM4E (0.41) | — | |
| SCHEMBL7400178 | 0.79 | KCNK3 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0668860-B1 | PYRAN-2-ONES AND 5,6-DIHYDROPYRAN-2-ONES USEFUL FOR TREATING HIV AND OTHER RETROVIRUSES | UPJOHN CO (US) | 2002-09-11 | — | — | EP | claimed |