Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7480255 | 0.84 | EDNRB (0.63) | EDNRBEDNRA | |
| SCHEMBL7477422 | 0.83 | EDNRB (0.58) | EDNRBEDNRA | |
| SCHEMBL795873 | 0.83 | EDNRB (0.54) | EDNRBEDNRA | |
| SCHEMBL7481169 | 0.82 | EDNRB (0.68) | EDNRBEDNRA | |
| SCHEMBL7487690 | 0.81 | EDNRB (0.61) | EDNRBEDNRA | |
| SCHEMBL8801730 | 0.81 | EDNRB (0.81) | EDNRBEDNRA | |
| SCHEMBL8660604 | 0.81 | EDNRB (0.57) | EDNRBEDNRA | |
| SCHEMBL7489110 | 0.80 | EDNRB (0.58) | EDNRBEDNRA | |
| SCHEMBL8657549 | 0.80 | EDNRB (0.80) | EDNRBEDNRA | |
| SCHEMBL8801001 | 0.80 | EDNRB (0.71) | EDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0959072-B1 | Sulfonamide derivative and process for preparing the same | TANABE SEIYAKU CO (JP) | 2002-09-25 | — | — | EP | claimed |
| EP-0959072-B1 | Sulfonamide derivative and process for preparing the same | TANABE SEIYAKU CO (JP) | 2002-09-25 | — | — | EP | disclosed |
| EP-0959072-A1 | Sulfonamide derivative and process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1999-11-24 | — | — | EP | disclosed |
| US-5739333-A | 4-SULFONAMIDO-6-ARYLOXY OR -AMINOALKYLENEOXY,-AMINO, OR -THIOPYRIMIDINES; ENDOLTHELIN ANTAGONISTS; HYPOTENSIVE AND ULCER AGENTS; ASTHMA; RAYNAUD DISEASE; CARDIOVASCULAR DISORDERS | TANABE SEIYAKU CO., LTD. (JP) | 1998-04-14 | — | — | US | disclosed |
| EP-0743307-A1 | Sulfonamide derivative and process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1996-11-20 | — | — | EP | disclosed |