SCHEMBL7477384

SCHEMBL7477384

Cc1cc(C)cc(NC(=O)OC(C)(C)C)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA9 Q16790 1/20 0.48
LCK P06239 1/20 0.45
HTT P42858 2/20 0.44
NPSR1 Q6W5P4 2/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
THRB P10828 1/20 0.44
GAA P10253 1/20 0.43
CYP17A1 P05093 2/20 0.43
LMNA P02545 1/20 0.43
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
HDAC3 O15379 1/20 0.42
HDAC4 P56524 1/20 0.42
HDAC1 Q13547 1/20 0.42
HDAC7 Q8WUI4 1/20 0.42
HDAC2 Q92769 1/20 0.42
HDAC10 Q969S8 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15156167 0.92 CA12 (0.43) CA12CA1CA9LCKHTT
SCHEMBL5866245 0.90 CA12 (0.44) CA12CA1CA9LCKGAA
SCHEMBL13833174 0.88 LCK (0.44) CA12CA1CA9LCKCYP17A1
SCHEMBL22081738 0.88 CA12 (0.43) CA12CA1CA9LCKHTT
SCHEMBL31093899 0.88 CA12 (0.43) CA12CA1CA9LCKHTT
SCHEMBL26162759 0.87 CYP17A1 (0.42) CA12CA1CA9LCKMEN1
SCHEMBL879946 0.87 KMT2A (0.45) CA12CA1CA9LCKHTT
SCHEMBL25923116 0.87 TPMT (0.48) CA12CA1CA9LCKMEN1
SCHEMBL24662539 0.85 CA12 (0.41) CA12CA1CA9LCKHTT
SCHEMBL6301414 0.85 CA12 (0.44) CA12CA1CA9LCKHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011152471-A2 RECHARGEABLE BATTERY, FUNCTIONAL POLYMER, AND METHOD FOR SYNTHESIS THEREOF 株式会社ポリチオン (JP) 2011-12-08 WO disclosed
EP-0930298-B1 FLUORINATED 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES BANYU PHARMA CO LTD (JP) 2002-12-18 EP disclosed
US-6040449-A USEFUL FOR FORMING FLUORINE CONTAINING 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES, USEFUL AS ANTAGONIST FOR MUSCARINIC M3 RECEPTORS AND LESS SIDE EFFECT BANYU PHARMACEUTICAL CO LTD (JP) 2000-03-21 US disclosed
US-5948792-A POTENT AND SELECTIVE ANTAGONISTS FOR MUSCARINIC M.SUB.3 RECEPTORS WITH LITTLE SIDE EFFECTS. BANYU PHARMACEUTICAL CO., LTD. (JP) 1999-09-07 US disclosed
EP-0930298-A1 FLUORINATED 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES BANYU PHARMACEUTICAL CO., LTD. (JP) 1999-07-21 EP disclosed