Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7902272 | 0.90 | KDM4E (0.32) | ALDH1A1 | |
| SCHEMBL8844328 | 0.88 | MEN1 (0.30) | MEN1ALDH1A1KMT2A | |
| SCHEMBL8844993 | 0.86 | MEN1 (0.35) | MEN1KMT2A | |
| SCHEMBL8844202 | 0.85 | TDP1 (0.31) | MEN1KMT2A | |
| SCHEMBL8844514 | 0.85 | TDP1 (0.31) | MEN1KMT2A | |
| SCHEMBL8845025 | 0.84 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL7475017 | 0.82 | HTR2A (0.30) | — | |
| SCHEMBL8844184 | 0.81 | TDP1 (0.31) | ALDH1A1 | |
| SCHEMBL8844676 | 0.80 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL8845019 | 0.80 | MEN1 (0.31) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0538297-B9 | ANTIVIRAL TETRAHYDROIMIDAZO 1,4]BENZODIAZEPIN-2-(THIO)ONES | JANSSEN PHARMACEUTICA NV (BE) | 2002-10-16 | — | — | EP | disclosed |
| EP-0538297-B1 | ANTIVIRAL TETRAHYDROIMIDAZO 1,4]BENZODIAZEPIN-2-(THIO)ONES | JANSSEN PHARMACEUTICA NV (BE) | 2001-09-19 | — | — | EP | disclosed |