Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CTSS | P25774 | 6/20 | 0.46 |
| ▸ | CTSL | P07711 | 3/20 | 0.46 |
| ▸ | CTSB | P07858 | 3/20 | 0.46 |
| ▸ | CTSK | P43235 | 5/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7477925 | 1.00 | AKT1 (0.51) | AKT1MEN1KMT2ACTSSCTSL | |
| SCHEMBL7463209 | 0.84 | KMT2A (0.55) | MEN1KMT2A | |
| SCHEMBL7463206 | 0.84 | KMT2A (0.55) | MEN1KMT2A | |
| SCHEMBL23035079 | 0.84 | AKT1 (0.50) | AKT1MEN1KMT2ACTSSCTSL | |
| SCHEMBL21563240 | 0.84 | AKT1 (0.50) | AKT1MEN1KMT2ACTSSCTSL | |
| SCHEMBL23035088 | 0.84 | AKT1 (0.50) | AKT1MEN1KMT2ACTSSCTSL | |
| SCHEMBL23035087 | 0.84 | AKT1 (0.50) | AKT1MEN1KMT2ACTSSCTSL | |
| Hydrochloric Acid SCHEMBL7638810 | 0.83 | KMT2A (0.54) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7705998 | 0.83 | KMT2A (0.54) | MEN1KMT2A | |
| SCHEMBL17784913 | 0.82 | AKT1 (0.48) | AKT1MEN1KMT2ACTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871619-B1 | PHENYL THIAZOLE DERIVATIVES WITH ANTI HERPES VIRUS PROPERTIES | BOEHRINGER INGELHEIM PHARMA (US) | 2002-11-06 | — | — | EP | disclosed |
| US-6057451-A | AMINOTHIAZOLE DERIVATIVES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2000-05-02 | — | — | US | disclosed |