⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19374490 | 0.75 | — | — | |
| SCHEMBL13211621 | 0.70 | TDP1 (0.36) | — | |
| SCHEMBL19722986 | 0.69 | — | — | |
| SCHEMBL24191916 | 0.65 | — | — | |
| SCHEMBL24913362 | 0.65 | — | — | |
| SCHEMBL5453687 | 0.64 | — | — | |
| SCHEMBL18715525 | 0.64 | — | — | |
| SCHEMBL8034111 | 0.64 | — | — | |
| SCHEMBL2912991 | 0.64 | — | — | |
| SCHEMBL23733647 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4268824-A1 | IMIDAZO[2,1-F][1,2,4]TRIAZINE DERIVATIVES USEFUL AS A MEDICAMENT | Manros Therapeutics (FR) | 2023-11-01 | — | — | EP | disclosed |
| EP-3415160-B1 | POLYPEPTIDES DERIVED FROM ENTEROCOCCUS AND THEIR USE FOR VACCINATION AND THE GENERATION OF THERAPEUTIC ANTIBODIES | KLINIKUM DER UNIV MUENCHEN (DE) | 2021-08-18 | — | — | EP | disclosed |
| EP-3394052-B1 | BICYCLIC HYDROXAMIC ACIDS USEFUL AS INHIBITORS OF MAMMALIAN HISTONE DEACETYLASE ACTIVITY | KANCERA AB (SE) | 2021-07-28 | — | — | EP | disclosed |
| EP-2915543-B1 | Polypeptides derived from Enterococcus and their use for vaccination and the generation of therapeutic antibodies | UNIV FREIBURG ALBERT LUDWIGS (DE) | 2018-05-09 | — | — | EP | disclosed |
| US-9657015-B2 | Substituted bicyclic dihydropyrimidinones and their use as inhibitors of neutrophil elastase activity | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2017-05-23 | — | — | US | disclosed |
| EP-0818512-B1 | Quinoline derivative and use of same | MITSUI CHEMICALS INC (JP) | 2002-10-02 | — | — | EP | disclosed |
| US-6407242-B1 | REACTING A PHTHALIMIDE COMPOUND WITH A QUINOLINE COMPOUND;ELECTROLUMINESCENCE | MITSUI CHEMICALS, INC. (JP) | 2002-06-18 | — | — | US | disclosed |
| US-6132640-A | ZINC COMPLEXES OF QUINOLINE | MITSUI CHEMICALS, INC. (JP) | 2000-10-17 | — | — | US | disclosed |
| EP-0818512-A1 | Quinoline derivative and use of same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1998-01-14 | — | — | EP | disclosed |
| US-4143149-A | CARDIOVASCULAR DISORDERS | BOEHRINGER MANNHEIM GMBH (DE) | 1979-03-06 | — | — | US | disclosed |