Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6177307 | 0.97 | TSHR (0.50) | TSHRHTTMEN1THRBKMT2A | |
| SCHEMBL6176446 | 0.97 | TSHR (0.50) | TSHRHTTMEN1THRBKMT2A | |
| SCHEMBL222083 | 0.94 | TSHR (0.52) | TSHRHTTMEN1THRBKMT2A | |
| SCHEMBL615987 | 0.94 | TSHR (0.52) | TSHRHTTMEN1THRBKMT2A | |
| SCHEMBL4632876 | 0.94 | TSHR (0.52) | TSHRHTTMEN1THRBKMT2A | |
| SCHEMBL11523839 | 0.94 | TSHR (0.52) | TSHRHTTMEN1THRBKMT2A | |
| SCHEMBL19445 | 0.94 | — | — | |
| SCHEMBL3794823 | 0.92 | HTT (0.56) | TSHRHTTMEN1THRBKMT2A | |
| SCHEMBL3797777 | 0.92 | HTT (0.56) | TSHRHTTMEN1THRBKMT2A | |
| SCHEMBL57546 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0769008-B1 | PYRAZOLE DERIVATIVES AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2002-05-22 | — | — | EP | disclosed |
| US-6339046-B1 | FOR CONTROLLING WEEDS | SYNGENTA INVESTMENT CORPORATION | 2002-01-15 | — | — | US | disclosed |
| US-6083881-A | Pyrazole derivatives as herbicides | NOVARTIS CORPORATION (US) | 2000-07-04 | — | — | US | disclosed |
| EP-0839808-A1 | Pyrazole derivatives, processes for their preparation, and their use as herbicides | Novartis AG (CH) | 1998-05-06 | — | — | EP | disclosed |
| EP-0769008-A1 | PYRAZOLE DERIVATIVES AS HERBICIDES | Novartis AG (CH) | 1997-04-23 | — | — | EP | disclosed |
| WO-1996001254-A1 | PYRAZOLE DERIVATIVES AS HERBICIDES | CIBA-GEIGY AG (CH) | 1996-01-18 | — | — | WO | disclosed |