Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10516243 | 0.81 | CYP2D6 (0.45) | KMT2AESR1SMN1; SMN2MEN1KDM4E | |
| SCHEMBL7485595 | 0.77 | GRM5 (0.45) | KMT2AESR1SMN1; SMN2MEN1KDM4E | |
| SCHEMBL8604716 | 0.75 | CA9 (0.69) | KMT2AESR1MEN1KDM4ECA1 | |
| SCHEMBL30231754 | 0.75 | CA9 (0.69) | KMT2AESR1MEN1KDM4ECA1 | |
| SCHEMBL7485228 | 0.74 | KMT2A (0.49) | KMT2AMEN1LMNAPABPC1ALDH1A1 | |
| SCHEMBL1251588 | 0.73 | SMN1; SMN2 (0.72) | KMT2ASMN1; SMN2MEN1KDM4ECA1 | |
| SCHEMBL30754216 | 0.73 | SMN1; SMN2 (0.72) | KMT2ASMN1; SMN2MEN1KDM4ECA1 | |
| SCHEMBL22379048 | 0.70 | CA12 (0.65) | KMT2AESR1SMN1; SMN2MEN1KDM4E | |
| SCHEMBL19773976 | 0.69 | KMT2A (0.68) | KMT2AESR1SMN1; SMN2MEN1KDM4E | |
| N-Phenyl-Phthalimide SCHEMBL123618 | 0.69 | KMT2A (0.68) | KMT2AESR1SMN1; SMN2MEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020120143-A1 | Process for the preparation of 2,3-pyridinedicarboximides | INTELLECTUAL PROPERTY DEPARTMENT, BASF AKTIENGESELLSCHAFT (DE) | 2002-08-29 | — | — | US | disclosed |
| EP-0812842-B1 | Process for the preparation of 5-(alkoxymethyl)-2,3-pyridine-dicarboximide compounds | BASF AG (DE) | 2002-03-27 | — | — | EP | disclosed |
| EP-0812843-B1 | Process for the preparation of 2,3-pyridinedicarboximides | BASF AG (DE) | 2002-01-30 | — | — | EP | disclosed |
| US-6316629-B1 | AS CHEMICAL INTERMEDIATES TO OBTAIN HERBICIDES | AMERICAN CYANAMID CO. | 2001-11-13 | — | — | US | disclosed |
| US-6034253-A | CHEMICAL INTERMEDIATE FOR HERBICIDE | AMERICA CYANAMID COMPANY (US) | 2000-03-07 | — | — | US | disclosed |
| US-5905154-A | CHEMICAL CONDENSATION OF OXIME WITH HALOMALEIMIDE FOR HERBICIDES | AMERICAN CYANAMID COMPANY (US) | 1999-05-18 | — | — | US | disclosed |
| US-5849916-A | Process for the preparation of 2,3-pyridinedicarboximides | AMERICAN CYANAMID COMPANY (US) | 1998-12-15 | — | — | US | disclosed |
| EP-0812842-A2 | Process for the preparation of 5-(alkoxymethyl)-2,3-pyridine-dicarboximide compounds | American Cyanamid Company (US) | 1997-12-17 | — | — | EP | disclosed |
| EP-0812843-A2 | Process for the preparation of 2,3-pyridinedicarboximides | American Cyanamid Company (US) | 1997-12-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020120143-A1 | Process for the preparation of 2,3-pyridinedicarboximides | PNPO, CHRNA9, NAPRT | KMT2A 1901/4885ESR1 4283/4885SMN1; SMN2 950/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.