⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL37486 | 0.97 | — | — | |
| SCHEMBL27546354 | 0.97 | CYP3A4 (0.46) | — | |
| Water SCHEMBL27610249 | 0.94 | — | — | |
| SCHEMBL28130290 | 0.87 | MAPT (0.42) | — | |
| SCHEMBL28101523 | 0.85 | CYP3A4 (0.39) | — | |
| SCHEMBL11833138 | 0.84 | TDP1 (0.49) | — | |
| SCHEMBL6570568 | 0.82 | MEN1 (0.44) | — | |
| SCHEMBL8038272 | 0.80 | CYP3A4 (0.39) | — | |
| SCHEMBL11524652 | 0.80 | CYP3A4 (0.36) | — | |
| SCHEMBL27669465 | 0.80 | TSHR (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6441019-B2 | E. G., 6-(3-CHLOROPHENYL)-1,4-DIHYDRO-4,4-DIMETHYL-2H-THIENO-(2,3-D)(1,3) OXAZINE-2-ONE; AGONISTS AND ANTAGONISTS OF THE PROGESTERONE RECEPTOR; INDUCING CONTRACEPTION AND TREATING OR PREVENTING BENIGN OR MALIGNANT NEOPLASTIC DISEASES | WYETH | 2002-08-27 | — | — | US | disclosed |
| US-6380178-B1 | CONTRACEPTION WHICH COMPRISES ADMINISTERING TO A FEMALE OF FOR 28 CONSECUTIVE DAYS: FIRST PHASE OF FROM 14 TO 24 DAILY DOSAGE UNITS OF A PROGESTATIONAL AGENT LEVONORGESTREL; SECOND PHASE OF FROM 1 TO 11 DAILY DOSAGE UNITS OF ANTIPROGESTIN COMPOUND | AMERICAN HOME PRODUCTS CORPORATION | 2002-04-30 | — | — | US | disclosed |
| EP-1185535-A1 | CYCLOCARBAMATE AND CYCLIC AMIDE DERIVATIVES | American Home Products Corporation (US) | 2002-03-13 | — | — | EP | disclosed |
| EP-1173253-A1 | CONTRACEPTIVE COMPOSITIONS CONTAINING CYCLIC CARBAMATES AND AMIDE DERIVATIVES | American Home Products Corporation (US) | 2002-01-23 | — | — | EP | disclosed |
| US-20020002173-A1 | Cyclocarbamate and cyclic amide derivatives | LIGAND PHARMACEUTICALS INCORPORATED | 2002-01-03 | — | — | US | disclosed |
| US-6306851-B1 | ADMINISTERING TO A MAMMAL A COMPOUND FOR BENIGN OR MALIGNANT NEOPLASTIC DISEASE IS SELECTED FROM UTERINE MYOMETRIAL FIBROIDS, ENDOMETRIOSIS, BENIGN PROSTATIC HYPERTROPHY; | AMERICAN HOME PRODUCTS CORPORATION | 2001-10-23 | — | — | US | disclosed |
| WO-2000066225-A1 | CONTRACEPTIVE COMPOSITIONS CONTAINING CYCLIC CARBAMATES AND AMIDE DERIVATIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-11-09 | — | — | WO | disclosed |
| WO-2000066591-A1 | CYCLOCARBAMATE AND CYCLIC AMIDE DERIVATIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-11-09 | — | — | WO | disclosed |