Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 20/20 | 0.87 |
| ▸ | GRIA2 | P42262 | 20/20 | 0.87 |
| ▸ | GRIA3 | P42263 | 20/20 | 0.87 |
| ▸ | GRIA4 | P48058 | 20/20 | 0.87 |
| ▸ | GRIK1 | P39086 | 15/20 | 0.87 |
| ▸ | GRIK2 | Q13002 | 15/20 | 0.87 |
| ▸ | GRIK5 | Q16478 | 15/20 | 0.87 |
| ▸ | GRIK3 | Q13003 | 14/20 | 0.87 |
| ▸ | GRIK4 | Q16099 | 14/20 | 0.87 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8675672 | 0.93 | GRIA1 (1.00) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL7479864 | 0.91 | GRIA1 (0.85) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8674238 | 0.84 | GRIA1 (0.84) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8674522 | 0.83 | GRIA1 (1.00) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8672085 | 0.83 | GRIA1 (1.00) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL7972520 | 0.82 | GRIA1 (1.00) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8686136 | 0.82 | GRIA1 (1.00) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8675872 | 0.80 | GRIA1 (1.00) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8612054 | 0.80 | GRIA1 (1.00) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8608737 | 0.79 | GRIA1 (0.87) | GRIA1GRIA2GRIA3GRIA4GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799224-B1 | QUINOXALINES AND DRUGS PREPARED THEREFROM | BASF AG (DE) | 2002-04-17 | — | — | EP | disclosed |
| US-5849743-A | Quinoxalines and drugs prepared therefrom | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-15 | — | — | US | disclosed |
| WO-1996019476-A1 | NOVEL QUINOXALINES AND DRUGS PREPARED THEREFROM | BASF AKTIENGESELLSCHAFT (DE) | 1996-06-27 | — | — | WO | disclosed |