Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 2/20 | 0.65 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.65 |
| ▸ | CACNA1C | Q13936 | 8/20 | 0.64 |
| ▸ | CACNA1F | O60840 | 7/20 | 0.64 |
| ▸ | CACNA1D | Q01668 | 7/20 | 0.64 |
| ▸ | CACNA1S | Q13698 | 7/20 | 0.64 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 6/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.63 |
| ▸ | MAPT | P10636 | 4/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.63 |
| ▸ | THPO | P40225 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7486357 | 0.98 | CACNA1C (0.67) | CACNA1BPDE1CCACNA1CCACNA1FCACNA1D | |
| SCHEMBL7480490 | 0.91 | MEN1 (0.65) | CACNA1BPDE1CCACNA1CCACNA1FCACNA1D | |
| SCHEMBL7485258 | 0.90 | CACNA1F (0.66) | CACNA1BPDE1CCACNA1CCACNA1FCACNA1D | |
| SCHEMBL7487761 | 0.89 | MEN1 (0.67) | CACNA1BPDE1CCACNA1CCACNA1FCACNA1D | |
| SCHEMBL7481094 | 0.88 | CACNA1C (0.68) | CACNA1BPDE1CCACNA1CCACNA1FCACNA1D | |
| SCHEMBL7415057 | 0.84 | CACNA1F (0.91) | CACNA1BPDE1CCACNA1CCACNA1FCACNA1D | |
| SCHEMBL7266660 | 0.84 | CACNA1F (0.91) | CACNA1BPDE1CCACNA1CCACNA1FCACNA1D | |
| SCHEMBL7480460 | 0.83 | CACNA1B (0.64) | CACNA1BPDE1CCACNA1CCACNA1FCACNA1D | |
| SCHEMBL3065410 | 0.83 | MEN1 (0.81) | CACNA1BPDE1CCACNA1CCACNA1FCACNA1D | |
| SCHEMBL3065413 | 0.83 | MEN1 (0.81) | CACNA1BPDE1CCACNA1CCACNA1FCACNA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0779277-B1 | 1,4-DIHYDROPYRIDINE DERIVATIVE | MERCIAN CORP (JP) | 2002-07-10 | — | — | EP | disclosed |
| EP-0779277-A1 | 1,4-DIHYDROPYRIDINE DERIVATIVE | MERCIAN CORPORATION (JP) | 1997-06-18 | — | — | EP | disclosed |