Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.37 |
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | F10 | P00742 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 4/20 | 0.33 |
| ▸ | ACHE | P22303 | 4/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7470901 | 0.91 | F10 (0.39) | DRD2F2F10DRD3ACHE | |
| SCHEMBL8564530 | 0.89 | F2 (0.38) | DRD2F2F10DRD3ACHE | |
| SCHEMBL8564532 | 0.89 | F2 (0.38) | DRD2F2F10DRD3ACHE | |
| SCHEMBL8562349 | 0.88 | F2 (0.39) | F2F10ACHE | |
| SCHEMBL8562341 | 0.88 | F2 (0.39) | F2F10ACHE | |
| Hydrochloric Acid SCHEMBL8562318 | 0.88 | F10 (0.38) | DRD2F2F10DRD3ACHE | |
| SCHEMBL8562653 | 0.87 | F10 (0.39) | DRD2F2F10ACHEPRSS1 | |
| SCHEMBL8562646 | 0.87 | F10 (0.39) | DRD2F2F10ACHEPRSS1 | |
| Hydrochloric Acid SCHEMBL8560749 | 0.87 | F2 (0.38) | F2F10ACHEPRSS1 | |
| Hydrochloric Acid SCHEMBL8560802 | 0.87 | F10 (0.38) | DRD2F2F10ACHEPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0777667-A1 | CYCLIC BENZAZEPINE UREA DERIVATIVES WITH AGGREGATION-INHIBITING EFFECT | Dr. Karl Thomae GmbH (DE) | 1997-06-11 | — | — | EP | disclosed |
| WO-1996005194-A1 | CYCLIC BENZAZEPINE UREA DERIVATIVES WITH AGGREGATION-INHIBITING EFFECT | DR. KARL THOMAE GMBH (DE) | 1996-02-22 | — | — | WO | disclosed |