Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 12/20 | 0.60 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.59 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.58 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15295162 | 0.89 | SMN1; SMN2 (0.60) | FFAR1NR1H4POLBALDH1A1EPHX2 | |
| SCHEMBL29092627 | 0.87 | POLB (0.50) | POLBALDH1A1MAPTHTT | |
| SCHEMBL659263 | 0.85 | NR1H4 (0.59) | FFAR1FFAR4NR1H4KEAP1ALDH1A1 | |
| SCHEMBL5652618 | 0.83 | FFAR1 (0.63) | FFAR1FFAR4NR1H4KEAP1ALDH1A1 | |
| SCHEMBL69746 | 0.82 | FFAR1 (0.81) | FFAR1FFAR4KEAP1CA1CA2 | |
| SCHEMBL4109710 | 0.82 | FFAR1 (0.53) | FFAR1FFAR4NR1H4KEAP1POLB | |
| SCHEMBL7328828 | 0.82 | POLB (0.53) | FFAR1FFAR4NR1H4KEAP1POLB | |
| SCHEMBL27906215 | 0.82 | EPHX2 (0.56) | FFAR1FFAR4NR1H4KEAP1POLB | |
| SCHEMBL5789 | 0.82 | CYP4F2 (0.48) | POLBMAPTHTTCA2 | |
| SCHEMBL5619 | 0.82 | POLB (0.46) | POLBALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229010-A1 | NOVEL DIARYLAMIDE DERIVATIVES AND USE THEREOF AS MEDICINES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |