Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.38 |
| ▸ | CCKBR | P32239 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.36 |
| ▸ | PRCP | P42785 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7480686 | 1.00 | NPC1 (0.40) | NPC1RAB9AL3MBTL1PTPN1GPBAR1 | |
| SCHEMBL7485949 | 0.82 | NPC1 (0.48) | NPC1RAB9AL3MBTL1GRM5XIAP | |
| SCHEMBL7485943 | 0.82 | NPC1 (0.48) | NPC1RAB9AL3MBTL1GRM5XIAP | |
| SCHEMBL7487828 | 0.82 | NPC1 (0.48) | NPC1RAB9AL3MBTL1GRM5XIAP | |
| SCHEMBL7479692 | 0.82 | NPC1 (0.43) | NPC1RAB9AL3MBTL1GPBAR1GRM5 | |
| SCHEMBL7477167 | 0.82 | NPC1 (0.43) | NPC1RAB9AL3MBTL1GPBAR1GRM5 | |
| SCHEMBL7477162 | 0.82 | NPC1 (0.43) | NPC1RAB9AL3MBTL1GPBAR1GRM5 | |
| SCHEMBL7475125 | 0.81 | NPC1 (0.45) | NPC1RAB9AL3MBTL1GPBAR1GRM5 | |
| SCHEMBL7480163 | 0.81 | NPC1 (0.45) | NPC1RAB9AL3MBTL1GPBAR1GRM5 | |
| SCHEMBL7475130 | 0.81 | NPC1 (0.45) | NPC1RAB9AL3MBTL1GPBAR1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1227090-A1 | AMINE DERIVATIVES | Tadeka Chemical Industries, Ltd. (JP) | 2002-07-31 | — | — | EP | disclosed |