Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRA | P16234 | 4/20 | 0.68 |
| ▸ | KDR | P35968 | 3/20 | 0.68 |
| ▸ | EGFR | P00533 | 1/20 | 0.65 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.61 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL558651 | 0.86 | PDGFRA (0.80) | PDGFRAKDRPDGFRB | |
| SCHEMBL7481076 | 0.82 | EGFR (0.78) | PDGFRAEGFRPDGFRB | |
| SCHEMBL14967568 | 0.82 | PDGFRA (0.70) | PDGFRAKDREGFRPDGFRB | |
| SCHEMBL4361045 | 0.82 | PDGFRA (0.66) | PDGFRAKDREGFRPDGFRB | |
| SCHEMBL19633823 | 0.82 | PDGFRA (0.52) | PDGFRAKDRPDGFRB | |
| SCHEMBL7486831 | 0.82 | PDGFRA (1.00) | PDGFRAKDR | |
| SCHEMBL5205515 | 0.81 | PDGFRA (0.62) | PDGFRAKDREGFRPDGFRB | |
| SCHEMBL5824446 | 0.81 | PDGFRA (0.60) | PDGFRAKDRPDGFRBABCG2 | |
| SCHEMBL7461659 | 0.81 | KDR (0.48) | PDGFRAKDREGFRABCG2 | |
| SCHEMBL21753535 | 0.81 | PDGFRA (0.59) | PDGFRAKDREGFRPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4662319-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | Integrate Bioscience LLC (US) | 2025-12-17 | — | — | EP | disclosed |
| WO-2024168301-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | FUNCTION ONCOLOGY, INC. (US) | 2024-08-15 | — | — | WO | disclosed |
| EP-0860433-B1 | QUINOLINE DERIVATIVES AND QUINAZOLINE DERIVATIVES INHIBITING AUTOPHOSPHORYLATION OF GROWTH FACTOR RECEPTOR ORIGINATING IN PLATELET AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | KIRIN BREWERY (JP) | 2002-07-03 | — | — | EP | disclosed |
| US-6143764-A | ETHER DERIVATIVES OF QUINOLINE, ANTITUMOR AGENTS | KIRIN BEER KABUSHIKI KAISHA (JP) | 2000-11-07 | — | — | US | disclosed |
| EP-0860433-A1 | QUINOLINE DERIVATIVES AND QUINAZOLINE DERIVATIVES INHIBITING AUTOPHOSPHORYLATION OF GROWTH FACTOR RECEPTOR ORIGINATING IN PLATELET AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | KIRIN BEER KABUSHIKI KAISHA (JP) | 1998-08-26 | — | — | EP | disclosed |