Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 20/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7475694 | 1.00 | TACR1 (0.58) | TACR1 | |
| SCHEMBL7473456 | 1.00 | TACR1 (0.58) | TACR1 | |
| SCHEMBL7478602 | 1.00 | TACR1 (0.58) | TACR1 | |
| SCHEMBL8194407 | 0.92 | TACR1 (0.48) | TACR1 | |
| SCHEMBL8195219 | 0.92 | TACR1 (0.48) | TACR1 | |
| SCHEMBL7482334 | 0.92 | TACR1 (0.48) | TACR1 | |
| SCHEMBL7477998 | 0.92 | TACR1 (0.48) | TACR1 | |
| SCHEMBL7480425 | 0.91 | TACR1 (0.47) | TACR1 | |
| SCHEMBL7485968 | 0.91 | TACR1 (0.47) | TACR1 | |
| SCHEMBL7483356 | 0.90 | TACR1 (0.47) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165540-A1 | TETRAHYDROPYRAN DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | MERCK SHARP & DOHME LTD. (GB) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000056728-A1 | TETRAHYDROPYRAN DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | MERCK SHARP & DOHME LIMITED (GB) | 2000-09-28 | — | — | WO | disclosed |
| WO-2000056727-A1 | TETRAHYDROPYRAN DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | MERCK SHARP & DOHME LIMITED (GB) | 2000-09-28 | — | — | WO | disclosed |