Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1F | O60840 | 8/20 | 0.76 |
| ▸ | CACNA1D | Q01668 | 8/20 | 0.76 |
| ▸ | CACNA1S | Q13698 | 8/20 | 0.76 |
| ▸ | CACNA1C | Q13936 | 8/20 | 0.76 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.73 |
| ▸ | MEN1 | O00255 | 4/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.71 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.71 |
| ▸ | MAPT | P10636 | 3/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.71 |
| ▸ | TSHR | P16473 | 2/20 | 0.71 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.71 |
| ▸ | THPO | P40225 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7755544 | 0.99 | CACNA1F (0.74) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL8295672 | 0.96 | CACNA1F (0.70) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL7482398 | 0.96 | CACNA1F (0.70) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL8297263 | 0.96 | CACNA1F (0.70) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| Hydrochloric Acid SCHEMBL10771661 | 0.89 | CACNA1F (0.77) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL7564216 | 0.88 | NR3C2 (0.69) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL10663707 | 0.87 | CACNA1F (0.84) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL11036485 | 0.87 | HIF1A (0.79) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL10747970 | 0.86 | CACNA1F (0.83) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL6725228 | 0.86 | CACNA1F (0.87) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0779277-B1 | 1,4-DIHYDROPYRIDINE DERIVATIVE | MERCIAN CORP (JP) | 2002-07-10 | — | — | EP | disclosed |
| EP-0657429-B1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE 1,4-DIHYDROPYRIDINE COMPOUNDS | MERCIAN CORP (JP) | 2001-04-11 | — | — | EP | disclosed |
| US-5760238-A | ANTIISCHEMIC AGENTS | MERCIAN CORPORATION (JP) | 1998-06-02 | — | — | US | disclosed |
| EP-0779277-A1 | 1,4-DIHYDROPYRIDINE DERIVATIVE | MERCIAN CORPORATION (JP) | 1997-06-18 | — | — | EP | disclosed |
| US-5635395-A | Optically active 1,4-dihydropyridine compounds and the microbial process for the stereoselection thereof | MERCIAN CORPORATION (JP) | 1997-06-03 | — | — | US | disclosed |
| EP-0657429-A1 | OPTICALLY ACTIVE 1,4-DIHYDROPYRIDINE COMPOUND AND PROCESS FOR PRODUCING THE SAME | MERCIAN CORPORATION (JP) | 1995-06-14 | — | — | EP | disclosed |