⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11768917 | 0.97 | — | — | |
| SCHEMBL8076384 | 0.97 | — | — | |
| SCHEMBL8077989 | 0.97 | — | — | |
| Diethylamine SCHEMBL8078238 | 0.81 | TP53 (0.35) | — | |
| SCHEMBL17061029 | 0.80 | — | — | |
| Pyridine SCHEMBL8078245 | 0.79 | TSHR (0.38) | — | |
| SCHEMBL28244105 | 0.75 | — | — | |
| SCHEMBL17696695 | 0.75 | — | — | |
| SCHEMBL28574527 | 0.73 | — | — | |
| SCHEMBL4487116 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 269 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705500-A2 | REAGENT USED IN DEPROTECTION OF 3'-O-AMINO POLYNUCLEOTIDES | DNA Script (FR) | 2026-03-11 | — | — | EP | claimed |
| WO-2024227846-A2 | REAGENT USED IN DEPROTECTION OF 3'-O-AMINO POLYNUCLEOTIDES | DNA SCRIPT (FR) | 2024-11-07 | — | — | WO | claimed |
| US-20240368656-A1 | REAGENTS AND METHODS USED IN DEPROTECTION OF 3'-O-AMINO POLYNUCLEOTIDES | DNA SCRIPT (FR) | 2024-11-07 | — | — | US | claimed |
| US-20180185487-A1 | METHOD TO ACHIEVE EXTENDED EXPRESSION OF DNA INFUSED INTO LIVER | IMMUSOFT CORPORATION | 2018-07-05 | — | — | US | claimed |
| US-20140141065-A1 | METHOD TO ACHIEVE EXTENDED EXPRESSION OF DNA INFUSED INTO LIVER | IMMUSOFT CORPORATION | 2014-05-22 | — | — | US | claimed |
| CN-100364544-C | Gelatin micro-particles carried with dichloromethylene diphosphonate, and its prepn. method | RUIJIN HOSPITAL ATTACHED TO SH (CN) | 2008-01-30 | — | — | CN | claimed |
| US-20070218116-A1 | Compositions and methods for the treatment of tumors and tumor metastases | SCHWENDENER RETO A | 2007-09-20 | — | — | US | claimed |
| US-20070044165-A1 | Non-human mammal model comprising heterologous nucleated cells - use for screening compounds | INSTITUT PASTEUR (FR) | 2007-02-22 | — | — | US | claimed |
| EP-1708566-A1 | NON-HUMAN MAMMAL MODEL COMPRISING HETEROLOGOUS NUCLEATED CELLS-USE FOR SCREENING COMPOUNDS | INSTITUT PASTEUR (FR) | 2006-10-11 | — | — | EP | claimed |
| EP-1701612-A2 | CHIMERIC MURINE MODEL COMPRISING HUMAN HEPATOCYTES USER FOR SCREENING COMPOUNDS | INSTITUT PASTEUR (FR) | 2006-09-20 | — | — | EP | claimed |
| US-6770260-B1 | MAMMAL MODEL CONTAINS A DECREASED LEVEL OF ENDOGENOUS MACROPHAGES SUFFICIENT TO REDUCE DEPLETION OF NON-AUTOLOGOUS HEMATOPOIETIC CELLS, ACHIEVED BY ADMINISTERING AN EFFECTIVE AMOUNT OF DICHLOROMETHYLENE DIPHOSPHONATE | NOVARTIS AG (CH) | 2004-08-03 | — | — | US | claimed |
| CN-1150200-C | Process for preparing methylene bisphosphonates | — | 2004-05-19 | — | — | CN | claimed |
| CN-1124130-C | Pharmaceutical formulation comprising a clodronate active ingredient and a silicified microcrystalline cellulose excipient | LEIRAS OY (FI) | 2003-10-15 | — | — | CN | claimed |
| CN-1121875-C | Pharmaceutical composition suitable for freeze drying | ASTRA PHARMA PROD (GB) | 2003-09-24 | — | — | CN | claimed |
| US-20030118637-A1 | Composition and method for treating autoimmune hemolytic anemia | NATIONAL JEWISH MEDICAL AND RESEARCH CENTER | 2003-06-26 | — | — | US | claimed |
| CN-1371383-A | Process for preparing methylene bisphosphonic and salts | ASTRAZENECA UK LTD (GB) | 2002-09-25 | — | — | CN | claimed |
| CN-1270516-A | Pharmaceutical preparation comprising colodronate as active ingredient and silicified microcrystalline cellulose as excipient | LEIRAS OY (FI) | 2000-10-18 | — | — | CN | claimed |
| US-5932563-A | Methods for treating spinal cord injury | OHIO STATE RESEARCH FOUNDATION (US) | 1999-08-03 | — | — | US | claimed |
| EP-0787003-A2 | USE OF MACROPHAGE DEPLETING AGENTS FOR PROLONGING THE SURVIVAL OF NON-AUTOLOGUS HEMATOPOIETIC CELL TRANSPLANTS AND ANIMAL MODEL ASSAY SYSTEMS | Novartis AG (CH) | 1997-08-06 | — | — | EP | claimed |
| WO-1995016452-A2 | USE OF MACROPHAGE DEPLETING AGENTS FOR PROLONGING THE SURVIVAL OF NON-AUTOLOGUS HEMATOPOIETIC CELL TRANSPLANTS AND ANIMAL MODEL ASSAY SYSTEMS | SYSTEMIX INC. (US) | 1995-06-22 | — | — | WO | claimed |