SCHEMBL74851

SCHEMBL74851

[CH2]n1ccnn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3070359 0.65 NOTUM (0.33)
SCHEMBL1727810 0.61
SCHEMBL28758681 0.61
SCHEMBL665313 0.61
SCHEMBL2842848 0.61
SCHEMBL23808321 0.60
SCHEMBL171550 0.60
SCHEMBL60018 0.60
SCHEMBL9697518 0.60
SCHEMBL2643021 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 589 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230339904-A1 ISOINDOLINONES, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS BIOTHERYX, INC. 2023-10-26 US claimed
CN-107709658-B Oxidation process 卡特克塞尔科技有限公司 2021-04-09 CN claimed
EP-3307940-B1 OXIDATIVE METHOD CATEXEL TECH LIMITED (GB) 2021-03-24 EP claimed
US-10815616-B2 Oxidative method CATEXEL TECHNOLOGIES LIMITED (GB) 2020-10-27 US claimed
EP-2185549-B1 ANTIMICROBIAL ORTHO-FLUOROPHENYL OXAZOLIDINONES FOR TREATMENT OF BACTERIAL INFECTIONS MICURX PHARMACEUTICALS INC (KY) 2018-10-03 EP claimed
US-20180094384-A1 OXIDATIVE METHOD CATEXEL B.V. (NL) 2018-04-05 US claimed
CN-107709658-A Method for oxidation 卡特克塞尔科技有限公司 2018-02-16 CN claimed
EP-2220048-B1 ARYL- AND HETEROARYLCARBONYL DERIVATIVES OF BENZOMORPHANES AND RELATED SCAFFOLDS, MEDICAMENTS CONTAINING SUCH COMPOUNDS AND THEIR USE BOEHRINGER INGELHEIM INT (DE) 2017-01-25 EP claimed
US-9505750-B2 5-aminocyclylmethyl-oxazolidin-2-one derivatives ACTELION PHARMACEUTICALS LTD. (CH) 2016-11-29 US claimed
US-9469632-B2 6-substituted-3H-1,3-benzothiazol-2-one compounds as TARP-gamma 8 dependent AMPA receptor antagonists ELI LILLY AND COMPANY (US) 2016-10-18 US claimed
CN-1325388-A Azacyclodepsipeptides and their use as parasiticides BAYER AG (DE) 2001-12-05 CN claimed
US-5866583-A Substituted 2,4-diaminopyrimidines HOFFMANN-LA ROCHE INC. (US) 1999-02-02 US claimed
EP-0853626-A1 SUBSTITUTED PHOSPHINIC COMPOUNDS AND THEIR USE AS PHARMACEUTICALS Novartis AG (CH) 1998-07-22 EP claimed
EP-0816379-A2 DNA binding oligomers BAYER AG (DE) 1998-01-07 EP claimed
WO-1997009335-A1 SUBSTITUTED PHOSPHINIC COMPOUNDS AND THEIR USE AS PHARMACEUTICALS NOVARTIS AG (CH) 1997-03-13 WO claimed
US-5446037-A Antiallergens; elastase inhibitors SYNPHAR LABORATORIES, INC. (CA) 1995-08-29 US claimed
CN-1082547-A Azabicyclic compounds FUJISAWA PHARMACEUTICAL CO (JP) 1994-02-23 CN claimed
WO-1993021186-A1 SUBSTITUTED 3-PYRROLIDINYLTHIO-CARBAPENEMS AS ANTIMICROBIAL AGENTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1993-10-28 WO claimed
EP-0045049-B1 ARYLAMINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MICROBICIDES CIBA-GEIGY AG (CH) 1985-06-26 EP claimed
EP-0045049-A2 Arylamine derivatives, process for their preparation and their use as microbicides CIBA-GEIGY AG (CH) 1982-02-03 EP claimed